Antiquitin Antibody (D-7): sc-376906
- Antiquitin Antibody (D-7) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 35-67 near the N-terminus of Antiquitin of human origin
- recommended for detection of Antiquitin of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and canine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Antiquitin Antibody (D-7) for WB applications. These reagents are now offered in bundles with Antiquitin Antibody (D-7) (see ordering information below).
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SEE ALSO...
Antiquitin (D-7) is a mouse monoclonal IgG1 antibody. Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. Antiquitin, also known as ALDH7A1 (aldehyde dehydrogenase 7 family, member A1), ATQ1, EPD or PDE, is a 539 amino acid protein that is highly expressed in ovary, heart, eye, kidney and ear tissue and plays an important role in the detoxification of lipid peroxidation- and alcohol metabolism-related aldehydes. Mutations in the gene encoding ALDH7A1 are the cause of pyridoxine-dependent epilepsy (PDE), a rare disorder that is characterized by seizures that begin at infancy and involve muscle rigidity, convulsions and loss of consciousness. Additionally, PDE is associated with poor muscle tone, hypothermia and irritability.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Antiquitin Antibody (D-7) | sc-376906 | 200 µg/ml | $322.00 | |||
Antiquitin Antibody (D-7): m-IgG Fc BP-HRP Bundle | sc-540663 | 200 µg Ab; 10 µg BP | $361.00 | |||
Antiquitin Antibody (D-7): m-IgG1 BP-HRP Bundle | sc-542280 | 200 µg Ab; 20 µg BP | $361.00 | |||
Antiquitin (D-7) Neutralizing Peptide | sc-376906 P | 100 µg/0.5 ml | $69.00 |