ANKRD52 Antibody (A-1): sc-398544
- ANKRD52 Antibody (A-1) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1043-1076 at the C-terminus of ANKRD52 of human origin
- Anti-ANKRD52 Antibody (A-1) is recommended for detection of ANKRD52 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ANKRD52 Antibody (A-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ANKRD52 Antibody (A-1) for WB applications. These reagents are now offered in bundles with ANKRD52 Antibody (A-1) (see ordering information below).
ANKRD52 Antibody (A-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects ANKRD52 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ANKRD52 antibody (A-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ANKRD52, also known as PP6-ARS-C, is a 1,076 amino acid phosphoprotein characterized by twenty-eight ankyrin repeats, which are crucial for its role as a regulatory subunit of protein phosphatase 6 (PP6). This holoenzyme is essential for various cellular processes, including cell cycle regulation and DNA damage response, highlighting ANKRD52′s importance in maintaining cellular homeostasis. Mutations in ankyrin genes can lead to severe genetic disorders, such as fatal cardiac arrhythmias and hereditary spherocytosis, underscoring ANKRD52′s significance in health and disease. Encoded by a gene located on human chromosome 12q13.2, ANKRD52 is conserved across multiple species, including chimpanzees, dogs, cows, mice, rats, chickens, and zebrafish, indicating a fundamental biological role.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ANKRD52 Antibody (A-1) References:
- Array painting reveals a high frequency of balanced translocations in breast cancer cell lines that break in cancer-relevant genes. | Howarth, KD., et al. 2008. Oncogene. 27: 3345-59. PMID: 18084325
- Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains. | Stefansson, B., et al. 2008. Biochemistry. 47: 1442-51. PMID: 18186651
- A muscle transcriptome analysis identifies positional candidate genes for a complex trait in pig. | Lobjois, V., et al. 2008. Anim Genet. 39: 147-62. PMID: 18366476
- Mapping of protein phosphatase-6 association with its SAPS domain regulatory subunit using a model of helical repeats. | Guergnon, J., et al. 2009. BMC Biochem. 10: 24. PMID: 19835610
- Diagnostic microRNA markers for screening sporadic human colon cancer and active ulcerative colitis in stool and tissue. | Ahmed, FE., et al. 2009. Cancer Genomics Proteomics. 6: 281-95. PMID: 19996134
- Microarray-based transcriptional profiling of Eimeria bovis-infected bovine endothelial host cells. | Taubert, A., et al. 2010. Vet Res. 41: 70. PMID: 20615380
- RNAi screen indicates widespread biological function for human natural antisense transcripts. | Faghihi, MA., et al. 2010. PLoS One. 5: PMID: 20957177
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ANKRD52 Antibody (A-1) | sc-398544 | 200 µg/ml | $322.00 | |||
ANKRD52 Antibody (A-1): m-IgG Fc BP-HRP Bundle | sc-530838 | 200 µg Ab; 10 µg BP | $361.00 | |||
ANKRD52 Antibody (A-1): m-IgGκ BP-HRP Bundle | sc-524384 | 200 µg Ab, 40 µg BP | $361.00 | |||
ANKRD52 Antibody (A-1): m-IgG1 BP-HRP Bundle | sc-544273 | 200 µg Ab; 20 µg BP | $361.00 | |||
ANKRD52 Antibody (A-1) AC | sc-398544 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ANKRD52 Antibody (A-1) HRP | sc-398544 HRP | 200 µg/ml | $322.00 | |||
ANKRD52 Antibody (A-1) FITC | sc-398544 FITC | 200 µg/ml | $336.00 | |||
ANKRD52 Antibody (A-1) PE | sc-398544 PE | 200 µg/ml | $349.00 | |||
ANKRD52 Antibody (A-1) Alexa Fluor® 488 | sc-398544 AF488 | 200 µg/ml | $364.00 | |||
ANKRD52 Antibody (A-1) Alexa Fluor® 546 | sc-398544 AF546 | 200 µg/ml | $364.00 | |||
ANKRD52 Antibody (A-1) Alexa Fluor® 594 | sc-398544 AF594 | 200 µg/ml | $364.00 | |||
ANKRD52 Antibody (A-1) Alexa Fluor® 647 | sc-398544 AF647 | 200 µg/ml | $364.00 | |||
ANKRD52 Antibody (A-1) Alexa Fluor® 680 | sc-398544 AF680 | 200 µg/ml | $364.00 | |||
ANKRD52 Antibody (A-1) Alexa Fluor® 790 | sc-398544 AF790 | 200 µg/ml | $364.00 | |||
ANKRD52 (A-1) Neutralizing Peptide | sc-398544 P | 100 µg/0.5 ml | $69.00 |