α-S1-casein Antibody (H-5): sc-373707

α-S1-casein Antibody (H-5) is a mouse monoclonal IgG2a antibody that detects α-S1-casein in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). α-S1-casein, also known as CSN1S1, CSN1, or CASA, is a 185 amino acid secreted protein specifically produced in the mammary gland and is a key member of the α-casein family. α-S1-casein exists as a disulfide-linked heterodimer with κ-casein, which is crucial for milk′s ability to transport calcium phosphate, essential minerals for the development and maintenance of bones and teeth. The structure of α-S1-casein allows for the formation of micelles that stabilize calcium phosphate, thereby enhancing bioavailability. α-S1-casein is encoded by a gene located on human chromosome 4, a region that not only encodes other casein family members but also contains significant gene deserts and is associated with various genetic disorders, including Huntington′s disease and polycystic kidney disease. Anti-α-S1-casein antibody (H-5) versatility in various applications makes this reagent an invaluable tool for researchers studying milk proteins and their roles in nutrition and health.

The preferred α-S1-casein antibody is α-S1-casein Antibody (D-8): sc-376961.