α/β centractin Antibody (E-5): sc-390632
- α/β centractin Antibody (E-5) is a mouse monoclonal IgG2b κ α/β centractin antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 218-241 within an internal region of α-centractin and β-centractin of human origin
- recommended for detection of α-centractin and β-centractin of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- TransCruz reagent for ChIP application (sc-390632 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for α/β centractin Antibody (E-5) for WB applications. These reagents are now offered in bundles with α/β centractin Antibody (E-5) (see ordering information below).
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α/β centractin Antibody (E-5) is a mouse monoclonal IgG2b kappa light chain antibody that detects the alpha/beta centractin protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). α/β centractin (E-5) antibody is available as the non-conjugated form. Centractin, a crucial component of the dynactin complex, plays a significant role in various cellular processes, including intracellular transport and mitosis. The dynactin complex, which consists of 10-11 distinct subunits, is essential for the proper functioning of dynein, a molecular motor protein responsible for transporting cellular cargo along microtubules. Centractin exists in multiple isoforms, with the α isoform, also known as actin-related protein 1 homolog A (Arp1), being the most abundant. The β isoform, or actin-related protein 1 homolog B, shares 90% identity with the α isoform, and together they are expressed in a ratio of 15:1. The structural integrity of the dynactin complex is maintained by the backbone filament composed of α/β-centractin, which is vital for the arrangement and function of other proteins within the complex. Understanding the dynamics of centractin and its interactions within the dynactin complex is essential for elucidating the mechanisms of cellular transport and division, making anti-α/β centractin antibody (E-5) a valuable tool for researchers studying these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α/β centractin Antibody (E-5) | sc-390632 | 200 µg/ml | $322.00 | |||
α/β centractin Antibody (E-5): m-IgG Fc BP-HRP Bundle | sc-538096 | 200 µg Ab; 10 µg BP | $361.00 | |||
α/β centractin Antibody (E-5): m-IgGκ BP-HRP Bundle | sc-535635 | 200 µg Ab; 40 µg BP | $361.00 | |||
α/β centractin Antibody (E-5): m-IgG2b BP-HRP Bundle | sc-549918 | 200 µg Ab; 10 µg BP | $361.00 | |||
α/β centractin (E-5) Neutralizing Peptide | sc-390632 P | 100 µg/0.5 ml | $69.00 | |||
α/β centractin Antibody (E-5) X | sc-390632 X | 200 µg/0.1 ml | $322.00 |