


ALK-1 Antibody (E-11) is a mouse monoclonal IgM antibody that detects ALK-1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ALK-1, also known as activin receptor-like kinase 1, plays a crucial role in the regulation of vascular development and homeostasis, making ALK-1 essential for maintaining normal blood vessel function. ALK-1 is primarily located on the surface of vascular endothelial cells, where ALK-1 mediates signaling pathways that influence angiogenesis and vascular remodeling. Proper functioning of ALK-1 is vital, as mutations in ALK-1 are implicated in hereditary hemorrhagic telangiectasia (HHT), a disorder characterized by abnormal blood vessel formation and increased risk of bleeding. By understanding the localization and function of ALK-1, researchers can better comprehend ALK-1′s role in vascular diseases and explore potential therapeutic targets. Anti-ALK-1 antibody (E-11) is an invaluable tool for studying this important protein and its implications in human health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ALK-1 Antibody (E-11) | sc-518147 | 200 µg/ml | $322.00 | |||
ALK-1 Antibody (E-11): m-IgGκ BP-HRP Bundle | sc-551132 | 200 µg Ab; 40 µg BP | $361.00 |