ALB/Albumin Antibody (F-8): sc-374670
- ALB/Albumin Antibody (F-8) is a mouse monoclonal IgG2a κ, cited in 8 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 559-591 near the C-terminus of serum albumin of mouse origin
- Anti-ALB/Albumin Antibody (F-8) is recommended for detection of ALB of mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ALB/Albumin Antibody (F-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ALB/Albumin Antibody (F-8) for WB and IHC(P) applications. These reagents are now offered in bundles with ALB/Albumin Antibody (F-8) (see ordering information below).
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ALB Antibody (F-8) is a mouse monoclonal IgG2a kappa light chain antibody engineered to recognize an epitope mapping between amino acids 559-591 near the C-terminus of mouse serum albumin (ALB), also known as mouse serum albumin. ALB (F-8) monoclonal antibody is validated for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA) applications specifically in mouse and rat samples. Serum albumin is the most abundant protein in blood plasma, synthesized in the liver′s hepatocytes, and plays a vital role in maintaining the colloidal osmotic pressure of blood, which is essential for regulating fluid balance between blood vessels and tissues. Located extracellularly in the bloodstream, albumin functions as a carrier protein, binding and transporting a wide range of ligands including water, fatty acids, calcium, sodium, bilirubin, hormones, potassium, and various drugs, thereby facilitating their distribution and availability throughout the body. The extracellular location of albumin is crucial as it allows efficient transport of these molecules, ensuring metabolic regulation and homeostasis. Additionally, albumin′s ability to bind and transport hormones like thyroxine underscores its importance in endocrine regulation. Post-translational modifications of albumin, such as glycation and oxidation, enhance its binding capacity and stability, allowing it to effectively perform its transport and regulatory functions under diverse physiological conditions. Mutations in the ALB gene can lead to disorders such as familial dysalbuminemic hyperthyroxinemia (FDH), which affects thyroid hormone binding and highlights the clinical significance of albumin′s functional interactions. Anti-ALB antibody (F-8) supports researchers in exploring albumin-related physiological processes and disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ALB/Albumin Antibody (F-8) | sc-374670 | 200 µg/ml | $322.00 | |||
ALB/Albumin Antibody (F-8): m-IgG Fc BP-HRP Bundle | sc-529795 | 200 µg Ab; 10 µg BP | $361.00 | |||
ALB/Albumin Antibody (F-8): m-IgGκ BP-HRP Bundle | sc-522810 | 200 µg Ab, 40 µg BP | $361.00 | |||
ALB/Albumin Antibody (F-8): m-IgG2a BP-HRP Bundle | sc-547381 | 200 µg Ab; 10 µg BP | $361.00 | |||
ALB/Albumin Antibody (F-8) AC | sc-374670 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ALB/Albumin Antibody (F-8) HRP | sc-374670 HRP | 200 µg/ml | $322.00 | |||
ALB/Albumin Antibody (F-8) FITC | sc-374670 FITC | 200 µg/ml | $336.00 | |||
ALB/Albumin Antibody (F-8) PE | sc-374670 PE | 200 µg/ml | $349.00 | |||
ALB/Albumin Antibody (F-8) Alexa Fluor® 488 | sc-374670 AF488 | 200 µg/ml | $364.00 | |||
ALB/Albumin Antibody (F-8) Alexa Fluor® 546 | sc-374670 AF546 | 200 µg/ml | $364.00 | |||
ALB/Albumin Antibody (F-8) Alexa Fluor® 594 | sc-374670 AF594 | 200 µg/ml | $364.00 | |||
ALB/Albumin Antibody (F-8) Alexa Fluor® 647 | sc-374670 AF647 | 200 µg/ml | $364.00 | |||
ALB/Albumin Antibody (F-8) Alexa Fluor® 680 | sc-374670 AF680 | 200 µg/ml | $364.00 | |||
ALB/Albumin Antibody (F-8) Alexa Fluor® 790 | sc-374670 AF790 | 200 µg/ml | $364.00 | |||
ALB/Albumin (F-8) Neutralizing Peptide | sc-374670 P | 100 µg/0.5 ml | $69.00 |