Adipsin Antibody (H-1): sc-271685
- Adipsin Antibody (H-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 152-206 mapping within an internal region of Adipsin of human origin
- recommended for detection of Adipsin of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Adipsin Antibody (H-1) for WB applications. These reagents are now offered in bundles with Adipsin Antibody (H-1) (see ordering information below).
QUICK LINKS
SEE ALSO...
Adipsin Antibody (H-1) is a mouse monoclonal IgG1 light chain antibody that detects Adipsin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Adipsin, also known as complement Factor D, plays a crucial role in the complement system, which is essential for immune response and inflammation regulation. This serine protease is primarily secreted by adipose tissue, where anti-Adipsin antibody (H-1) can detect its involvement in the cleavage of complement factor B, facilitating the activation of the alternative pathway of the complement system. The importance of Adipsin extends beyond its enzymatic function; Adipsin monoclonal antibody (H-1) has helped reveal its role in metabolic processes and potential influence on obesity-related conditions. Notably, while low levels of Adipsin have been observed in obese mice with hypothalamic defects, the relationship between Adipsin expression and obesity in humans remains an area of ongoing research. Adipsin (H-1) antibody provides a valuable tool for studying this protein in various biological contexts, enhancing our understanding of its implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Adipsin Antibody (H-1) References:
- Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue. | White, RT., et al. 1992. J Biol Chem. 267: 9210-3. PMID: 1374388
- An immune responsive complement factor D/adipsin and kallikrein-like serine protease (PoDAK) from the olive flounder Paralichthys olivaceus. | Kong, HJ., et al. 2009. Fish Shellfish Immunol. 27: 486-92. PMID: 19591942
- Complement factor D derived from epicardial adipose tissue participates in cardiomyocyte apoptosis after myocardial infarction by mediating PARP-1 activity. | Hao, S., et al. 2023. Cell Signal. 101: 110518. PMID: 36351508
- Quantification of the zymogenicity and the substrate-induced activity enhancement of complement factor D. | Dani, R., et al. 2023. Front Immunol. 14: 1197023. PMID: 37283768
- Dominant-negative HNF1α mutant promotes liver steatosis and inflammation by regulating hepatic complement factor D. | Liu, M., et al. 2023. iScience. 26: 108018. PMID: 37841581
- The Role and Potential Mechanism of Complement Factor D in Fibromyalgia Development. | Lei, X., et al. 2023. J Pain Res. 16: 4337-4351. PMID: 38145036
- Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy. | Jankauskas, SS., et al. 2024. Mil Med Res. 11: 1. PMID: 38167325
- Urinary complement factor D is increased in primary malignant hypertension: a single-center, cross-sectional study. | Cheng, Y., et al. 2024. Sci Rep. 14: 16253. PMID: 39009768
- Adipsin improves diabetic hindlimb ischemia through SERPINE1 dependent angiogenesis. | Zhang, X., et al. 2024. Cardiovasc Diabetol. 23: 429. PMID: 39623437
- Modest release of adipsin/factor D by liposuction when using the superwet or tumescent technique. | Samdal, F., et al. 1997. Plast Reconstr Surg. 99: 1591-4; discussion 1595-6. PMID: 9145127
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Adipsin Antibody (H-1) | sc-271685 | 200 µg/ml | $322.00 | |||
Adipsin Antibody (H-1): m-IgG Fc BP-HRP Bundle | sc-537681 | 200 µg Ab; 10 µg BP | $361.00 | |||
Adipsin Antibody (H-1): m-IgGκ BP-HRP Bundle | sc-535024 | 200 µg Ab; 40 µg BP | $361.00 | |||
Adipsin Antibody (H-1): m-IgG1 BP-HRP Bundle | sc-545303 | 200 µg Ab; 20 µg BP | $361.00 |