Nicotinic Acetylcholine Receptor epsilon/CHRNE Antibody (D-6): sc-376826
- Nicotinic Acetylcholine Receptor epsilon/CHRNE Antibody (D-6) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 465-494 at the C-terminus of AChRε of mouse origin
- recommended for detection of AChRε of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Nicotinic Acetylcholine Receptor epsilon/CHRNE Antibody (D-6) for WB applications. These reagents are now offered in bundles with Nicotinic Acetylcholine Receptor epsilon/CHRNE Antibody (D-6) (see ordering information below).
AChRε Antibody (D-6) is a mouse monoclonal IgG2a antibody that detects AChRε in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AChRε, also known as CMS1D, CMS1E, CMS2A, FCCMS, SCCMS, or CHRNE, is a 493 amino acid multi-pass membrane protein that plays a crucial role in neuromuscular transmission by forming part of the nicotinic acetylcholine receptor complex. This receptor is essential for muscle contraction, as AChRε mediates the binding of acetylcholine at the neuromuscular junction, leading to the opening of ion channels that allow the influx of sodium ions and the subsequent depolarization of the muscle cell membrane. Proper functioning of AChRε is vital for muscle strength and coordination, and dysfunction is associated with congenital myasthenic syndromes, which can lead to severe muscle weakness and fatigue. Anti-AChRε antibody (D-6) enables investigation of receptor expression and function in various experimental settings.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor epsilon/CHRNE Antibody (D-6) | sc-376826 | 200 µg/ml | $316.00 | |||
Nicotinic Acetylcholine Receptor epsilon/CHRNE Antibody (D-6): m-IgG Fc BP-HRP Bundle | sc-538004 | 200 µg Ab; 10 µg BP | $354.00 | |||
Nicotinic Acetylcholine Receptor epsilon/CHRNE Antibody (D-6): m-IgGκ BP-HRP Bundle | sc-535516 | 200 µg Ab; 40 µg BP | $354.00 | |||
Nicotinic Acetylcholine Receptor epsilon/CHRNE Antibody (D-6): m-IgG2a BP-HRP Bundle | sc-548180 | 200 µg Ab; 10 µg BP | $354.00 | |||
Nicotinic Acetylcholine Receptor epsilon/CHRNE (D-6) Neutralizing Peptide | sc-376826 P | 100 µg/0.5 ml | $68.00 |