Date published: 2026-4-24

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AChR α 4 Antibodies

Santa Cruz Biotechnology features a diverse variety of AChR α 4 monoclonal antibodies for research focused on understanding the alpha-4 subunit of the acetylcholine receptor. Multiple detection methods are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The AChR α 4 subunit is crucial for the formation of functional nicotinic acetylcholine receptors, which play a significant role in neurotransmission and synaptic plasticity. AChR α 4 is involved in various physiological processes, including muscle contraction and cognitive functions, making it a vital target for research in neurobiology and pharmacology. Research on AChR α 4 can provide insights into neurological disorders and potential therapeutic interventions. Scientists studying neurotransmitter systems often investigate AChR α 4's role in synaptic signaling and neural circuit development. Understanding AChR α 4 function has implications for developing treatments for conditions affecting cholinergic neurotransmission. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of acetylcholine receptor biology and its impact on human health.

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AChR α 4 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 Antibody (A-6)

sc-74519mouse IgG1 κ342-474 (h)WB, IP, IF, IHC(P), ELISAm, r, h
8
(7)

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 Antibody (299)

sc-65862rat IgG1(r)WB, IP, IFm, r, h and chicken
3
(1)

AChR α 4 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 Double Nickase Plasmid (h)

sc-401605-NIChGene KnockoutPuromycin0
(0)

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 Double Nickase Plasmid (h2)

sc-401605-NIC-2hGene KnockoutPuromycin0
(0)

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 CRISPR/Cas9 KO Plasmid (m)

sc-418954mGene KnockoutGFP0
(0)

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 HDR Plasmid (m)

sc-418954-HDRmHomology Directed RepairPuromycin0
(0)

AChR α 4 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 CRISPR Activation Plasmid (h)

sc-401605-ACThGene ActivationPuro, Blast, Hygro0
(0)

AChR α 4 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 siRNA (h)

sc-42528hGene SilencingN/A
1
(0)

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 shRNA Plasmid (h)

sc-42528-SHhGene SilencingPuromycin
1
(0)

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 shRNA (h) Lentiviral Particles

sc-42528-VhGene SilencingPuromycin
1
(0)

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 siRNA (m)

sc-42529mGene SilencingN/A0
(0)

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 shRNA Plasmid (m)

sc-42529-SHmGene SilencingPuromycin0
(0)

Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 shRNA (m) Lentiviral Particles

sc-42529-VmGene SilencingPuromycin0
(0)