AChR α 4 Activators
Items 1 to 10 of 16 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates Protein Kinase C (PKC), which can influence signaling pathways that lead to the activation of PEBP2β. | ||||||
Cytisine | 485-35-8 | sc-203015 sc-203015A | 5 mg 25 mg | $56.00 $190.00 | ||
Cytisine is a selective agonist for the alpha-4 subtype of nicotinic acetylcholine receptors, showcasing unique binding dynamics that enhance receptor activation. Its structural conformation allows for specific interactions with the receptor's ligand-binding domain, promoting distinct signaling pathways. The compound exhibits rapid kinetics in receptor engagement, leading to a swift modulation of synaptic transmission. Additionally, its lipophilic characteristics contribute to effective membrane permeability, influencing its bioavailability in various environments. | ||||||
RJR 2403 oxalate | 183288-99-5 | sc-204884 sc-204884A | 10 mg 50 mg | $189.00 $785.00 | 1 | |
RJR 2403 oxalate acts as a potent modulator of the alpha-4 nicotinic acetylcholine receptors, characterized by its ability to stabilize receptor conformations that favor enhanced signaling. Its unique molecular structure facilitates specific hydrogen bonding and hydrophobic interactions, which influence receptor affinity and activation kinetics. The compound's distinct electronic properties allow for effective charge distribution, impacting its interaction dynamics and overall efficacy in receptor modulation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases intracellular cAMP levels, potentially enhancing signaling pathways that activate PEBP2β. | ||||||
TC 2559 difumarate | 212332-35-9 | sc-203707 sc-203707A | 10 mg 50 mg | $185.00 $781.00 | ||
TC 2559 difumarate exhibits unique characteristics as an alpha-4 nicotinic acetylcholine receptor modulator, primarily through its ability to engage in selective molecular interactions. Its structural configuration promotes specific electrostatic interactions that enhance receptor binding affinity. Additionally, the compound's kinetic profile reveals a distinctive rate of receptor activation, influenced by its conformational flexibility, which may lead to varied signaling outcomes in biological systems. | ||||||
Desformylflustrabromine hydrochloride | 951322-11-5 | sc-358800 sc-358800A | 10 mg 50 mg | $175.00 $645.00 | ||
Desformylflustrabromine hydrochloride exhibits a unique affinity for the alpha-4 nicotinic acetylcholine receptor, characterized by its intricate binding interactions that alter receptor dynamics. The presence of halogen atoms enhances its electronic distribution, facilitating specific conformational changes in the receptor. This compound's kinetic behavior reveals a complex mechanism of action, influencing neurotransmitter release and modulating synaptic activity through distinct molecular pathways. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin activates the PI3K/AKT pathway, which might indirectly influence the activation of PEBP2β. | ||||||
Sazetidine A dihydrochloride | 820231-95-6 | sc-203256 | 1 mg | $186.00 | ||
Sazetidine A dihydrochloride demonstrates a selective interaction with the alpha-4 nicotinic acetylcholine receptor, showcasing a unique binding profile that stabilizes specific receptor conformations. Its structural features promote distinct electrostatic interactions, influencing receptor activation and desensitization kinetics. The compound's behavior in various environments highlights its ability to modulate ion channel dynamics, contributing to nuanced alterations in cellular signaling pathways. | ||||||
4-Acetyl-1,1-dimethylpiperazinium iodide | 75667-84-4 | sc-203473 sc-203473A | 10 mg 50 mg | $115.00 $473.00 | ||
4-Acetyl-1,1-dimethylpiperazinium iodide demonstrates a notable selectivity for the alpha-4 nicotinic acetylcholine receptor, engaging in specific electrostatic interactions that stabilize the receptor-ligand complex. This compound facilitates unique conformational changes in the receptor, influencing ion channel dynamics and modulating synaptic activity. Its reaction kinetics are characterized by rapid binding and dissociation rates, enabling fine-tuning of receptor responses in various biological contexts. | ||||||
3-Bromocytisine | 207390-14-5 | sc-361077 sc-361077A | 10 mg 50 mg | $179.00 $760.00 | ||
3-Bromocytisine exhibits a selective affinity for the alpha-4 nicotinic acetylcholine receptor, characterized by its unique molecular interactions that enhance receptor-ligand binding stability. This compound influences allosteric modulation, leading to altered receptor conformations that affect ion permeability. Its kinetic profile reveals distinct reaction rates, allowing for precise control over receptor activation and subsequent downstream signaling events, thereby impacting neuronal excitability and synaptic transmission. | ||||||