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20S Proteasome α5 Antibody (D-9) is a mouse monoclonal IgG1 antibody that detects PSMA5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PSMA5 is a crucial component of the 26S proteasome, which plays a vital role in maintaining cellular homeostasis by degrading unnecessary or damaged proteins through proteolysis. This process is essential for regulating various cellular functions, including cell cycle, signal transduction, and response to oxidative stress. The 20S core particle, where actual degradation occurs, is composed of multiple subunits that form a cylindrical structure, allowing for selective entry of target proteins while preventing unregulated access. PSMA5 contributes to structural integrity of the proteasome and is involved in assembly of the complex, ensuring efficient protein turnover. Anti-PSMA5 antibody (D-9) enables researchers to gain insights into proteasome activity and implications in various diseases, including cancer and neurodegenerative disorders, where proteasome function is often compromised.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
20S Proteasome α5 Antibody (D-9) | sc-271378 | 200 µg/ml | $316.00 | |||
20S Proteasome α5 Antibody (D-9): m-IgG Fc BP-HRP Bundle | sc-537625 | 200 µg Ab; 10 µg BP | $354.00 | |||
20S Proteasome α5 Antibody (D-9): m-IgGκ BP-HRP Bundle | sc-534944 | 200 µg Ab; 40 µg BP | $354.00 | |||
20S Proteasome α5 Antibody (D-9): m-IgG1 BP-HRP Bundle | sc-545265 | 200 µg Ab; 20 µg BP | $354.00 |