MyoD Antibody (E-1): sc-377186

MyoD Antibody (E-1) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect Myogenic Differentiation 1 (MyoD), also known as MRF1, a pivotal transcription factor within the Myogenic Regulatory Factors (MRFs) family that includes myogenin, Myf5, and MRF4. Anti-MyoD antibody (E-1) is raised against amino acids 1-318 of mouse MyoD, targeting a region that encompasses the basic helix-loop-helix (bHLH) domains, which are essential for dimerization with E proteins and binding to E-box sequences in DNA. The structural configuration of MyoD, particularly its bHLH domains, is critical for its role in regulating the transcription of muscle-specific genes, thereby driving muscle cell differentiation and development. Located in the nucleus, MyoD facilitates the activation of genes necessary for muscle regeneration by interacting with E proteins such as E2A, IF2, and HEB. MyoD monoclonal antibody (E-1) is recommended for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA) applications in both mouse and rat species. Available in both conjugated and non-conjugated forms, anti-MyoD antibody (E-1) offers versatility for various experimental protocols, making MyoD monoclonal antibody (E-1) a valuable tool for researchers exploring the molecular mechanisms of myogenesis, muscle biology, and related fields.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-MyoD Antibody (E-1) has 11 citations in a variety of scientific publications.

Primary antibodies like Anti-MyoD Antibody (E-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

MyoD Antibody (E-1) Specifications

Alternate Product Name: MyoD

Product Clone Name: E-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-318

Epitope Target: MyoD

Epitope Species: mouse

Product Reactivity/Detection: MyoD

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 11 citations in various scientific publications

Available Conjugates/Forms for MyoD Antibody (E-1): X: TransCruz Reagent