Date published: 2026-7-19

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BRCA Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of BRCA Antibodies for research focused on understanding BRCA1 and BRCA2 in cellular processes. BRCA Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). BRCA1 and BRCA2 maintain genomic stability and are integral to DNA repair mechanisms. Mutations in BRCA genes significantly increase the risk of breast and ovarian cancers, highlighting their importance in cancer research and therapeutic development. Research focusing on BRCA1 and BRCA2 continues to reveal new insights about their roles in DNA damage response pathways. Understanding BRCA gene expression patterns helps identify potential therapeutic targets for cancer treatment. Ongoing studies of BRCA1 and BRCA2 contribute to developing more effective cancer prevention strategies. Current research explores how BRCA mutations affect cellular responses to various cancer treatments. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of BRCA proteins and their impact on cancer biology.

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BRCA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

BRCA1 Antibody (D-9)

sc-6954mouse IgG2a κ1843-1862 (h)WB, IP, IF, ELISAh
450
(53)

BRCA1 Antibody (C-11)

sc-514797mouse IgG1 κ1564-1863 (h)WB, IP, IF, IHC(P), ELISAh
1
(0)

BRCA1 Antibody (287.17)

sc-135732mouse IgG2b κ(m)WB, IP, IF, IHC(P), ELISAm, r, h
11
(1)

BRCA1 Antibody (GLK-2)

sc-56030mouse IgM κ1839-1863 (h)WB, IP, IF, IHC(P)h
1
(1)

BRCA2 Antibody (3D12)

sc-293185mouse IgG3 κ3319-3418 (h)WB, IP, ELISAh
10
(5)

BRCA2 Antibody (1643CT739.91.87)

sc-517316mouse IgG1 κ251-495 (h)WBh

new

(0)

BRCA2 Antibody (184H2N)

sc-517636mouse IgG1 κ(h)WBh

new

(0)

Phospho-Specific BRCA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-BRCA1 Antibody (G-4)

sc-166793mouse IgG1 κSer 988 (h)WB, IP, IF, ELISAh
1
(4)

BRCA siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BRAT1 siRNA (h)

sc-89333hGene SilencingN/A0
(0)

BRAT1 shRNA Plasmid (h)

sc-89333-SHhGene SilencingPuromycin0
(0)

BRAT1 shRNA (h) Lentiviral Particles

sc-89333-VhGene SilencingPuromycin0
(0)

BRAT1 siRNA (m)

sc-140723mGene SilencingN/A0
(0)

BRAT1 shRNA Plasmid (m)

sc-140723-SHmGene SilencingPuromycin0
(0)

BRAT1 shRNA (m) Lentiviral Particles

sc-140723-VmGene SilencingPuromycin0
(0)

BRCA1 siRNA (h)

sc-29219hGene SilencingN/A
21
(1)

BRCA1 siRNA (h2)

sc-44247hGene SilencingN/A0
(0)

BRCA1 shRNA Plasmid (h)

sc-29219-SHhGene SilencingPuromycin
21
(1)

BRCA1 shRNA Plasmid (h2)

sc-44247-SHhGene SilencingPuromycin0
(0)

BRCA1 shRNA (h) Lentiviral Particles

sc-29219-VhGene SilencingPuromycin
21
(1)

BRCA1 shRNA (h2) Lentiviral Particles

sc-44247-VhGene SilencingPuromycin0
(0)

BRCA1 siRNA (m)

sc-29824mGene SilencingN/A
3
(0)

BRCA1 shRNA Plasmid (m)

sc-29824-SHmGene SilencingPuromycin
3
(0)

BRCA1 shRNA (m) Lentiviral Particles

sc-29824-VmGene SilencingPuromycin
3
(0)

BRCA2 siRNA (h)

sc-29825hGene SilencingN/A
14
(0)

BRCA2 shRNA Plasmid (h)

sc-29825-SHhGene SilencingPuromycin
14
(0)

BRCA2 shRNA (h) Lentiviral Particles

sc-29825-VhGene SilencingPuromycin
14
(0)

BRCA2 siRNA (m)

sc-29826mGene SilencingN/A0
(0)

BRCA2 shRNA Plasmid (m)

sc-29826-SHmGene SilencingPuromycin0
(0)

BRCA2 shRNA (m) Lentiviral Particles

sc-29826-VmGene SilencingPuromycin0
(0)

BRCA CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

BRCA1 CRISPR/Cas9 KO Plasmid (h)

sc-400093Gene Knockouth0
(0)

BRCA1 HDR Plasmid (h)

sc-400093-HDRHomology Directed Repairh0
(0)

BRCA1 CRISPR/Cas9 KO Plasmid (m)

sc-419362Gene Knockoutm0
(0)

BRCA1 HDR Plasmid (m)

sc-419362-HDRHomology Directed Repairm0
(0)

BRCA1 CRISPR/Cas9 KO Plasmid (r)

sc-437320Gene Knockoutr0
(0)

BRCA1 HDR Plasmid (r)

sc-437320-HDRHomology Directed Repairr0
(0)

BRCA2 CRISPR/Cas9 KO Plasmid (h)

sc-400700Gene Knockouth0
(0)

BRCA2 HDR Plasmid (h)

sc-400700-HDRHomology Directed Repairh0
(0)

BRCA2 CRISPR/Cas9 KO Plasmid (m)

sc-419363Gene Knockoutm0
(0)

BRCA2 HDR Plasmid (m)

sc-419363-HDRHomology Directed Repairm0
(0)

BRCA CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

BRAT1 Double Nickase Plasmid (h)

sc-415146-NICGene Knockouth0
(0)

BRAT1 Double Nickase Plasmid (h2)

sc-415146-NIC-2Gene Knockouth0
(0)

BRCA1 Double Nickase Plasmid (h)

sc-400093-NICGene Knockouth0
(0)

BRCA1 Double Nickase Plasmid (h2)

sc-400093-NIC-2Gene Knockouth0
(0)

BRCA1 Double Nickase Plasmid (m)

sc-419362-NICGene Knockoutm0
(0)

BRCA1 Double Nickase Plasmid (m2)

sc-419362-NIC-2Gene Knockoutm0
(0)

BRCA1 Double Nickase Plasmid (r)

sc-437320-NICGene Knockoutr0
(0)

BRCA1 Double Nickase Plasmid (r2)

sc-437320-NIC-2Gene Knockoutr0
(0)

BRCA2 Double Nickase Plasmid (h)

sc-400700-NICGene Knockouth0
(0)

BRCA2 Double Nickase Plasmid (h2)

sc-400700-NIC-2Gene Knockouth0
(0)

BRCA2 Double Nickase Plasmid (m)

sc-419363-NICGene Knockoutm0
(0)

BRCA2 Double Nickase Plasmid (m2)

sc-419363-NIC-2Gene Knockoutm0
(0)

BRCA CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

BRCA1 CRISPR Activation Plasmid (h)

sc-400093-ACTGene Activationh0
(0)

BRCA1 CRISPR Activation Plasmid (h2)

sc-400093-ACT-2Gene Activationh0
(0)

BRCA1 Lentiviral Activation Particles (h)

sc-400093-LACGene Activationh0
(0)

BRCA1 Lentiviral Activation Particles (h2)

sc-400093-LAC-2Gene Activationh0
(0)

BRCA1 CRISPR Activation Plasmid (m)

sc-419362-ACTGene Activationm0
(0)

BRCA1 CRISPR Activation Plasmid (m2)

sc-419362-ACT-2Gene Activationm0
(0)

BRCA2 CRISPR Activation Plasmid (h)

sc-400700-ACTGene Activationh0
(0)

BRCA2 CRISPR Activation Plasmid (h2)

sc-400700-ACT-2Gene Activationh0
(0)

BRCA2 Lentiviral Activation Particles (h)

sc-400700-LACGene Activationh0
(0)

BRCA2 Lentiviral Activation Particles (h2)

sc-400700-LAC-2Gene Activationh0
(0)