Date published: 2025-9-11

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SOX15 Inibitori

SOX15 inhibitors are a class of chemical compounds designed to specifically target and inhibit the activity of SOX15, a protein encoded by the SOX15 gene. SOX15, or SRY-box transcription factor 15, is a member of the SOX (SRY-related HMG-box) family of transcription factors, which play crucial roles in regulating gene expression during development and differentiation. SOX15 is involved in various developmental processes, including muscle development and differentiation, where it acts by binding to specific DNA sequences and regulating the transcription of target genes. This regulation is vital for the proper formation and function of tissues during embryogenesis and in maintaining the homeostasis of adult tissues.

Structurally, SOX15 inhibitors can vary widely, encompassing small molecules, peptides, or larger biomolecules that are engineered to interact specifically with the DNA-binding domain or other critical regions of the SOX15 protein. These inhibitors typically function by preventing SOX15 from binding to its target DNA sequences, thereby blocking its ability to regulate gene transcription. By inhibiting SOX15, these compounds can disrupt the transcriptional networks controlled by this factor, leading to changes in the expression of genes involved in cellular differentiation and development. The study of SOX15 inhibitors is crucial for understanding the regulatory mechanisms underlying SOX15's role in gene expression and its impact on developmental processes. Research into these inhibitors provides valuable insights into the broader implications of transcription factor regulation in cellular biology, highlighting the importance of precise control of gene expression in maintaining cellular identity and function. By exploring the effects of SOX15 inhibition, scientists can gain a deeper understanding of the intricate networks of gene regulation and the role of transcription factors in orchestrating the complex processes of development and differentiation.

VEDI ANCHE...

Nome del prodottoCAS #Codice del prodottoQuantitàPrezzoCITAZIONIValutazione

Triciribine

35943-35-2sc-200661
sc-200661A
1 mg
5 mg
$102.00
$138.00
14
(1)

Blocca l'attivazione di Akt, che in seguito downregola l'espressione di SOX (fattore di trascrizione SRY-box) attraverso la via PI3K/Akt.

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$80.00
$212.00
$408.00
48
(1)

Inibisce il recettore TGF-β di tipo I, impedendo l'upregulation indotta da TGF-β di SOX (fattore di trascrizione SRY-box) nelle cellule della cresta neurale.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

Inibisce la proteina chinasi associata a Rho (ROCK), influenzando la migrazione delle cellule della cresta neurale e probabilmente i processi correlati a SOX (fattore di trascrizione SRY-box).

Kaempferol

520-18-3sc-202679
sc-202679A
sc-202679B
25 mg
100 mg
1 g
$97.00
$212.00
$500.00
11
(1)

Riduce l'espressione di SOX (fattore di trascrizione SRY-box) modulando le vie di segnalazione MAPK, che svolgono un ruolo nello sviluppo delle cellule della cresta neurale.

5-Iodotubercidin

24386-93-4sc-3531
sc-3531A
1 mg
5 mg
$150.00
$455.00
20
(2)

Inibisce l'adenosina chinasi, determinando un aumento dei livelli di adenosina che può modulare le vie di segnalazione correlate a SOX (fattore di trascrizione SRY-box).