AOS-1 Activators
The chemical class of AOS-1 Activators (SAE1 Activators) consists of compounds that influence the SUMOylation pathway, a critical post-translational modification process in which AOS-1/SAE1 plays a significant role. Spectomycin B1 is notable for its ability to inhibit SUMOylation, which can indirectly enhance the functional activity of AOS-1/SAE1 by altering the dynamics of this pathway. Similarly, ML-792, as a selective inhibitor of the SUMO E1 enzyme, can modulate the availability and activity of AOS-1/SAE1 within the SUMOylation pathway.
Additionally, 2-D08, by inhibiting general SUMOylation processes, can indirectly influence AOS-1/SAE1's activity. Tannic Acid, with its inhibitory effect on protein SUMOylation, and Pyridone 6, a JAK inhibitor, may also contribute to the altered functional dynamics of AOS-1/SAE1. Embelin and NSC 632839, though not direct activators, have been shown to influence the SUMOylation pathway, potentially enhancing the role of AOS-1/SAE1.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ML-792 | 1644342-14-2 | sc-507423 | 10 mg | $398.00 | ||
A selective inhibitor for SUMO E1, which may indirectly increase the functional role of AOS-1/SAE1 in the pathway. | ||||||
2-D08 | 144707-18-6 | sc-507405 | 5 mg | $150.00 | ||
A small molecule that inhibits SUMOylation, potentially leading to enhanced AOS-1/SAE1 activity in the pathway. | ||||||
Gallotannin | 1401-55-4 | sc-202619 sc-202619A sc-202619B sc-202619C sc-202619D sc-202619E sc-202619F | 1 g 10 g 100 g 250 g 1 kg 2.5 kg 5 kg | $26.00 $37.00 $67.00 $78.00 $234.00 $536.00 $983.00 | 12 | |
Known to inhibit protein SUMOylation, which could indirectly affect the functional activity of AOS-1/SAE1. | ||||||
JAK Inhibitor I | 457081-03-7 | sc-204021 sc-204021A | 500 µg 1 mg | $156.00 $339.00 | 59 | |
A JAK inhibitor that might indirectly influence SUMOylation processes and AOS-1/SAE1 activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, could modulate stress response pathways indirectly affecting SUMOylation and AOS-1/SAE1 activity. | ||||||
Embelin | 550-24-3 | sc-201555 sc-201555A | 10 mg 50 mg | $89.00 $339.00 | 5 | |
A small molecule that inhibits XIAP, also known to influence SUMOylation pathways, potentially enhancing AOS-1/SAE1 activity. | ||||||
NSC 632839 hydrochloride | 157654-67-6 | sc-204138 sc-204138A | 10 mg 50 mg | $119.00 $465.00 | ||
Inhibits deubiquitinating enzymes, could indirectly affect SUMOylation processes involving AOS-1/SAE1. | ||||||