RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. POLR2G (DNA-directed RNA polymerase II subunit G), also known as RPB7, hRPB19 or hsRPB7, is the seventh largest subunit of RNA polymerase II. It is required for the transcription initiation phase of Pol II. POLR2G forms a subcomplex with the RPB4 subunit. This subcomplex protrudes from the Pol II core complex and, in the closed conformation, functions to prevent double stranded DNA from entering the active site.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps POLR2G (G-9) | sc-393890 | 200 µg/ml | $316.00 | |||
POLR2G (G-9): m-IgG Fc BP-HRP Kit | sc-538333 | 200 µg Ab; 10 µg BP | $354.00 | |||
POLR2G (G-9): m-IgGκ BP-HRP Kit | sc-535921 | 200 µg Ab; 40 µg BP | $354.00 | |||
POLR2G (G-9): m-IgG2a BP-HRP Kit | sc-548272 | 200 µg Ab; 10 µg BP | $354.00 |