RNA polymerase II (Pol II) is a multi-subunit complex responsible for catalyzing the transcription of DNA into RNA. POLR2E (polymerase (RNA) II (DNA directed) polypeptide E), also designated RPB5, XAP4, RPABC1, hRPB25 or hsRPB5, is a 210 amino acid nuclear protein belonging to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family. POLR2E is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR2E is a component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes. The Pol complexes synthesize both mRNA and ribosomal RNA precursors, many functional non-coding RNAs and small RNAs including 5S rRNA and tRNAs. POLR2E interacts with TFIIF RAP 30 and is important for the association between Pol II and TFIIF.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps POLR2E (C-10) | sc-390902 | 200 µg/ml | $316.00 | |||
POLR2E (C-10): m-IgG Fc BP-HRP Kit | sc-540868 | 200 µg Ab; 10 µg BP | $354.00 | |||
POLR2E (C-10): m-IgG1 BP-HRP Kit | sc-542430 | 200 µg Ab; 20 µg BP | $354.00 | |||
POLR2E (C-10) peptide neutralisant | sc-390902 P | 100 µg/0.5 ml | $68.00 |