PBGD Antibody (H-11): sc-166842
- PBGD Antibody (H-11) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 349-361 at the C-terminus of PBGD of human origin
- recommended for detection of PBGD of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PBGD Antibody (H-11) for WB applications. These reagents are now offered in bundles with PBGD Antibody (H-11) (see ordering information below).
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SEE ALSO...
PBGD Antibody (H-11) is a mouse monoclonal IgG2b antibody that detects porphobilinogen deaminase (PBGD) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PBGD plays a crucial role in the heme synthesis pathway, catalyzing the conversion of porphobilinogen into hydroxymethylbilane, which is a key intermediate in the production of heme, an essential component of hemoglobin and various enzymes. The proper functioning of PBGD is vital, as deficiencies can lead to acute intermittent porphyria (AIP), a serious inherited disorder characterized by neurological dysfunctions, abdominal pain, and elevated levels of porphobilinogen and aminolevulinic acid in the urine. Understanding the structure of PBGD is important because multiple domains facilitate enzymatic activity and interactions with other proteins in the heme biosynthesis pathway. PBGD (H-11) antibody is an invaluable tool for researchers studying the implications of PBGD in metabolic disorders and the broader context of heme metabolism.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PBGD Antibody (H-11) | sc-166842 | 200 µg/ml | $322.00 | |||
PBGD Antibody (H-11): m-IgG Fc BP-HRP Bundle | sc-537536 | 200 µg Ab; 10 µg BP | $361.00 | |||
PBGD Antibody (H-11): m-IgGκ BP-HRP Bundle | sc-534832 | 200 µg Ab; 40 µg BP | $361.00 | |||
PBGD Antibody (H-11): m-IgG2b BP-HRP Bundle | sc-549886 | 200 µg Ab; 10 µg BP | $361.00 | |||
PBGD (H-11) Neutralizing Peptide | sc-166842 P | 100 µg/0.5 ml | $69.00 |