ACCÈS RAPIDE AUX LIENS
Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ERK 3 (G-2) | sc-393371 | 200 µg/ml | $316.00 | |||
ERK 3 (G-2): m-IgGκ BP-HRP Kit | sc-535765 | 200 µg Ab; 40 µg BP | $354.00 | |||
ERK 3 (G-2): m-IgG2b BP-HRP Kit | sc-549477 | 200 µg Ab; 10 µg BP | $354.00 | |||
ERK 3 (G-2) peptide neutralisant | sc-393371 P | 100 µg/0.5 ml | $68.00 |