Date published: 2026-7-21

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SMG CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. SMG gene silencers are available as SMG CRISPR/Cas9 Knockout plasmids and SMG Double Nickase Plasmids. SMG CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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SMG CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

SMG1 CRISPR/Cas9 KO Plasmid (h)

sc-404760Gene Knockouth0
(0)

SMG5 CRISPR/Cas9 KO Plasmid (h)

sc-406989Gene Knockouth0
(0)

SMG8 CRISPR/Cas9 KO Plasmid (h)

sc-408902Gene Knockouth0
(0)

SMG6 CRISPR/Cas9 KO Plasmid (m)

sc-430478Gene Knockoutm0
(0)

SMG1 CRISPR/Cas9 KO Plasmid (m)

sc-433296Gene Knockoutm0
(0)

SMG1 HDR Plasmid (h)

sc-404760-HDRHomology Directed Repairh0
(0)

SMG5 HDR Plasmid (h)

sc-406989-HDRHomology Directed Repairh0
(0)

SMG8 HDR Plasmid (h)

sc-408902-HDRHomology Directed Repairh0
(0)

SMG6 HDR Plasmid (m)

sc-430478-HDRHomology Directed Repairm0
(0)

SMG1 HDR Plasmid (m)

sc-433296-HDRHomology Directed Repairm0
(0)

SMG CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

SMG5 Double Nickase Plasmid (h)

sc-406989-NICGene Knockouth0
(0)

SMG8 Double Nickase Plasmid (h)

sc-408902-NICGene Knockouth0
(0)

SMG5 Double Nickase Plasmid (h2)

sc-406989-NIC-2Gene Knockouth0
(0)

SMG8 Double Nickase Plasmid (h2)

sc-408902-NIC-2Gene Knockouth0
(0)

SMG CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

SMG1 CRISPR Activation Plasmid (h)

sc-404760-ACTGene Activationh0
(0)

SMG5 CRISPR Activation Plasmid (h)

sc-406989-ACTGene Activationh0
(0)

SMG8 CRISPR Activation Plasmid (h)

sc-408902-ACTGene Activationh0
(0)

SMG5 CRISPR Activation Plasmid (h2)

sc-406989-ACT-2Gene Activationh0
(0)

SMG8 CRISPR Activation Plasmid (h2)

sc-408902-ACT-2Gene Activationh0
(0)

SMG5 Lentiviral Activation Particles (h)

sc-406989-LACGene Activationh0
(0)