Date published: 2026-6-6

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SMG Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of SMG Antibodies for studying SMG proteins, which play a crucial role in RNA metabolism and gene expression regulation. SMG Antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SMG proteins are essential for the surveillance and degradation of mRNA, ensuring cellular homeostasis and proper gene expression. Their involvement in the nonsense-mediated decay pathway highlights their significance in preventing the accumulation of faulty transcripts, which can lead to various diseases. Understanding SMG protein function is vital for advancing research in molecular biology and therapeutic development. SMG proteins have emerged as key regulators in multiple cellular pathways, influencing development, stress response, and disease progression. Research into SMG protein function continues to reveal new insights about cellular regulation and potential therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of RNA metabolism and gene expression regulation.

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SMG Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SMG1 Antibody (E-4)

sc-374557mouse IgG1 κ3358-3657 (h)WB, IP, IF, ELISAm, r, h
1
(4)

SMG1 Antibody (6-RE13)

sc-135563mouse IgG2a κ2922-3032 (h)WB, IP, IF, IHC(P), ELISAh
5
(2)

SMG CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMG1 CRISPR/Cas9 KO Plasmid (h)

sc-404760hGene KnockoutGFP0
(0)

SMG1 HDR Plasmid (h)

sc-404760-HDRhHomology Directed RepairPuromycin0
(0)

SMG1 CRISPR/Cas9 KO Plasmid (m)

sc-433296mGene KnockoutGFP0
(0)

SMG1 HDR Plasmid (m)

sc-433296-HDRmHomology Directed RepairPuromycin0
(0)

SMG5 CRISPR/Cas9 KO Plasmid (h)

sc-406989hGene KnockoutGFP0
(0)

SMG5 HDR Plasmid (h)

sc-406989-HDRhHomology Directed RepairPuromycin0
(0)

SMG5 Double Nickase Plasmid (h)

sc-406989-NIChGene KnockoutPuromycin0
(0)

SMG5 Double Nickase Plasmid (h2)

sc-406989-NIC-2hGene KnockoutPuromycin0
(0)

SMG6 CRISPR/Cas9 KO Plasmid (m)

sc-430478mGene KnockoutGFP0
(0)

SMG6 HDR Plasmid (m)

sc-430478-HDRmHomology Directed RepairPuromycin0
(0)

SMG8 HDR Plasmid (h)

sc-408902-HDRhHomology Directed RepairPuromycin0
(0)

SMG8 Double Nickase Plasmid (h)

sc-408902-NIChGene KnockoutPuromycin0
(0)

SMG8 Double Nickase Plasmid (h2)

sc-408902-NIC-2hGene KnockoutPuromycin0
(0)

SMG CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMG1 CRISPR Activation Plasmid (h)

sc-404760-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMG5 CRISPR Activation Plasmid (h)

sc-406989-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMG5 CRISPR Activation Plasmid (h2)

sc-406989-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG5 Lentiviral Activation Particles (h)

sc-406989-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMG8 CRISPR Activation Plasmid (h)

sc-408902-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMG8 CRISPR Activation Plasmid (h2)

sc-408902-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMG1 siRNA (h)

sc-76521hGene SilencingN/A0
(0)

SMG1 shRNA Plasmid (h)

sc-76521-SHhGene SilencingPuromycin0
(0)

SMG1 shRNA (h) Lentiviral Particles

sc-76521-VhGene SilencingPuromycin0
(0)

SMG1 siRNA (m)

sc-76522mGene SilencingN/A0
(0)

SMG1 shRNA Plasmid (m)

sc-76522-SHmGene SilencingPuromycin0
(0)

SMG1 shRNA (m) Lentiviral Particles

sc-76522-VmGene SilencingPuromycin0
(0)

SMG5 siRNA (h)

sc-61567hGene SilencingN/A0
(0)

SMG5 shRNA Plasmid (h)

sc-61567-SHhGene SilencingPuromycin0
(0)

SMG5 shRNA (h) Lentiviral Particles

sc-61567-VhGene SilencingPuromycin0
(0)

SMG5 siRNA (m)

sc-61568mGene SilencingN/A0
(0)

SMG5 shRNA Plasmid (m)

sc-61568-SHmGene SilencingPuromycin0
(0)

SMG5 shRNA (m) Lentiviral Particles

sc-61568-VmGene SilencingPuromycin0
(0)

SMG6 siRNA (h)

sc-61569hGene SilencingN/A0
(0)

SMG6 shRNA Plasmid (h)

sc-61569-SHhGene SilencingPuromycin0
(0)

SMG6 shRNA (h) Lentiviral Particles

sc-61569-VhGene SilencingPuromycin0
(0)

SMG6 siRNA (m)

sc-61570mGene SilencingN/A0
(0)

SMG6 shRNA Plasmid (m)

sc-61570-SHmGene SilencingPuromycin0
(0)

SMG6 shRNA (m) Lentiviral Particles

sc-61570-VmGene SilencingPuromycin0
(0)

SMG7 siRNA (h)

sc-61571hGene SilencingN/A0
(0)

SMG7 shRNA Plasmid (h)

sc-61571-SHhGene SilencingPuromycin0
(0)

SMG7 shRNA (h) Lentiviral Particles

sc-61571-VhGene SilencingPuromycin0
(0)

SMG7 siRNA (m)

sc-61572mGene SilencingN/A0
(0)

SMG7 shRNA Plasmid (m)

sc-61572-SHmGene SilencingPuromycin0
(0)

SMG7 shRNA (m) Lentiviral Particles

sc-61572-VmGene SilencingPuromycin0
(0)

SMG8 siRNA (h)

sc-93833hGene SilencingN/A0
(0)

SMG8 shRNA Plasmid (h)

sc-93833-SHhGene SilencingPuromycin0
(0)

SMG8 shRNA (h) Lentiviral Particles

sc-93833-VhGene SilencingPuromycin0
(0)

SMG9 siRNA (h)

sc-97314hGene SilencingN/A0
(0)

SMG9 shRNA Plasmid (h)

sc-97314-SHhGene SilencingPuromycin0
(0)

SMG9 shRNA (h) Lentiviral Particles

sc-97314-VhGene SilencingPuromycin0
(0)