Date published: 2026-7-13

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Prion Protein Antibodies

Santa Cruz Biotechnology provides a broad selection of Prion Protein monoclonal antibodies for various research applications. Prion Protein Antibodies are optimized for techniques such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Prion proteins play a critical role in neurodegenerative diseases, including Creutzfeldt-Jakob disease and other transmissible spongiform encephalopathies. The misfolding and aggregation of prion proteins can lead to severe neurological damage, making prion protein research essential for understanding disease mechanisms and developing potential therapeutic strategies. The ability to accurately detect and analyze prion proteins is crucial for advancing research in this field. Prion protein monoclonal antibodies enable researchers to investigate protein expression patterns, cellular localization, and protein-protein interactions. Prion Protein Antibodies targeting prion proteins support detailed molecular studies of neurodegenerative processes. Santa Cruz Biotechnology monoclonal antibodies for prion protein research contribute to advancing scientific understanding of neurodegenerative diseases and potential therapeutic developments.

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Prion Protein Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PrP Antibody (5B2)

sc-47730mouse IgG1 κFL (m)WB, IP, IF, IHC(P), FCM, ELISAmammalian
5
(5)

PrP Antibody (8B4)

sc-47729mouse IgG1 κFL (m)WB, IP, IF, IHC(P), FCM, ELISAmammalian
17
(4)

PrP Antibody (AH6)

sc-69896mouse IgG2a κFL (ovine)WB, IP, FCM, ELISAm, r, h, ovine, hamster and deer
4
(3)

PrP Antibody (6G3)

sc-52969mouse IgG1130-150 (h)WB, IPm, r, h, bovine, ovine and deer

new

(2)

PrP Antibody (G-12)

sc-398451mouse IgG1 κ217-232 (h)WB, IP, IF, ELISAm, r, h
1
(2)

PrP Antibody (H-8)

sc-393165mouse IgG2a κ1-253 (h)WB, IP, IF, IHC(P), ELISAh
1
(3)

Prion Protein siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PrP siRNA (h)

sc-36318hGene SilencingN/A
11
(0)

PrP shRNA Plasmid (h)

sc-36318-SHhGene SilencingPuromycin
11
(0)

PrP shRNA (h) Lentiviral Particles

sc-36318-VhGene SilencingPuromycin
11
(0)

PrP siRNA (m)

sc-36319mGene SilencingN/A
2
(0)

PrP shRNA Plasmid (m)

sc-36319-SHmGene SilencingPuromycin
2
(0)

PrP shRNA (m) Lentiviral Particles

sc-36319-VmGene SilencingPuromycin
2
(0)

Prion Protein CRISPR Knockout (KO) and HDR Plasmids

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PrP CRISPR/Cas9 KO Plasmid (h2)

sc-401061-KO-2Gene Knockouth0
(0)

PrP HDR Plasmid (h2)

sc-401061-HDR-2Homology Directed Repairh0
(0)

PrP CRISPR/Cas9 KO Plasmid (m2)

sc-422422-KO-2Gene Knockoutm0
(0)

PrP HDR Plasmid (m2)

sc-422422-HDR-2Homology Directed Repairm0
(0)

Prion Protein CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PrP Double Nickase Plasmid (h)

sc-401061-NICGene Knockouth0
(0)

PrP Double Nickase Plasmid (h2)

sc-401061-NIC-2Gene Knockouth0
(0)

Prion Protein CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PrP CRISPR Activation Plasmid (h)

sc-401061-ACTGene Activationh0
(0)

PrP CRISPR Activation Plasmid (h2)

sc-401061-ACT-2Gene Activationh0
(0)