Periphilin 1 is a protein encoded by the "PPHLN1" gene in humans. It is involved in multiple cellular processes, particularly in the formation and maintenance of the cellular cytoskeleton and in the regulation of gene expression.As its name suggests, periphilin 1 is localized primarily in the periphery of the cell, where it interacts with various components of the cytoskeleton. The cytoskeleton is a network of fibers that provides structural support to the cell, facilitates cellular movement, and plays a role in intracellular transport and cell division. By interacting with the cytoskeleton, periphilin 1 contributes to maintaining the structural integrity and dynamic nature of cells.
In addition to its structural role, periphilin 1 is involved in the regulation of gene expression. It has been found to associate with transcription factors and components of the transcription machinery, suggesting a role in modulating the transcription of specific genes. This regulation of gene expression is vital for various cellular functions, including differentiation, response to external stimuli, and cell cycle control.Periphilin 1 has also been studied in the context of its involvement in certain pathological conditions. Alterations in its expression or function have been associated with some skin disorders, where it may affect the structure and function of epidermal cells.Overall, periphilin 1 is a multifunctional protein with roles in maintaining cellular structure and regulating gene expression. Its diverse functions highlight its importance in fundamental cellular processes and its relevance in certain diseases.
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| Nom du produit | CAS # | Ref. Catalogue | Quantité | Prix HT | CITATIONS | Classement |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibiteur de l'ADN méthyltransférase, la 5-Azacytidine modifie la structure de la chromatine et peut avoir un impact indirect sur le rôle de la Periphiline 1 dans la régulation de la transcription. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
En tant qu'inhibiteur de l'histone désacétylase, la trichostatine A affecte le remodelage de la chromatine, influençant potentiellement la fonction de la periphiline 1. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Un autre inhibiteur d'histone désacétylase, SAHA, peut affecter la structure de la chromatine et avoir un impact indirect sur l'activité de Periphilin 1. | ||||||
RGFP966 | 1357389-11-7 | sc-507300 | 5 mg | $115.00 | ||
Un inhibiteur spécifique de HDAC3, RGFP966, peut indirectement affecter la structure de la chromatine et la fonction de Periphilin 1. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
Un inhibiteur sélectif d'HDAC, le MS-275, peut influencer le remodelage de la chromatine et potentiellement affecter l'activité de la Periphiline 1. | ||||||
Inhibiteur Histone Lysine Methyltransferase Inhibitor | 935693-62-2 free base | sc-202651 | 5 mg | $148.00 | 4 | |
Un inhibiteur de l'histone méthyltransférase G9a, BIX-01294, peut modifier la méthylation des histones, ce qui pourrait avoir un impact sur la fonction de la Periphiline 1. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $260.00 $925.00 | 5 | |
Le C646, un inhibiteur de l'histone acétyltransférase, peut affecter indirectement la périphiline 1 en influençant l'acétylation des histones et la structure de la chromatine. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
Un inhibiteur de la bromodomaine BET, JQ1, peut avoir un impact sur l'architecture de la chromatine et influencer indirectement l'activité de Periphilin 1. | ||||||
Methylstat | 1310877-95-2 | sc-507374 | 10 mg | $480.00 | ||
Un inhibiteur d'histone déméthylase contenant le domaine Jumonji C, Methylstat, peut indirectement influencer l'activité de Periphilin 1 en affectant la méthylation des histones. | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $120.00 | 5 | |
Inhibiteur ciblant l'histone méthyltransférase SUV39H1, le Chaetocin peut indirectement influencer le rôle de Periphilin 1 dans l'organisation de la chromatine. | ||||||