Glutamine-rich 1, also known as QRICH1, is a protein that in humans is encoded by the QRICH1 gene. This protein is characterized by a high content of glutamine residues, which are amino acids represented by the letter "Q" in protein sequences, hence the "Q-rich" designation.its glutamine-rich nature provides some clues about its potential roles. Proteins with glutamine-rich regions are often involved in protein-protein interactions and can form aggregates, which play roles in various cellular processes but can also be associated with certain diseases, such as neurodegenerative disorders.
Bioinformatic analysis suggests that QRICH1 contains a DUF3712 domain, a protein domain of unknown function found in several eukaryotic proteins. The presence of this domain suggests that QRICH1 may participate in widespread biological processes or pathways.In terms of disease associations, studies have suggested a potential link between QRICH1 and certain types of cancer. A 2020 study found that QRICH1 was upregulated in ovarian cancer tissues and that its silencing inhibited ovarian cancer cell proliferation and induced apoptosis. However, these initial findings need further validation.
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| Nom du produit | CAS # | Ref. Catalogue | Quantité | Prix HT | CITATIONS | Classement |
|---|---|---|---|---|---|---|
L-Glutamine | 56-85-9 | sc-391013 sc-391013C sc-391013A sc-391013D sc-391013B | 100 g 250 g 1 kg 5 kg 10 kg | $36.00 $46.00 $97.00 $372.00 $719.00 | 2 | |
La L-Glutamine sert de substrat primaire pour les protéines riches en glutamine, ce qui peut améliorer leur fonction. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $291.00 $566.00 | ||
Le glutamate peut être converti en glutamine, ce qui favorise indirectement les protéines riches en glutamine. | ||||||
FCM Lysing solution (1x) | sc-3621 | 150 ml | $61.00 | 8 | ||
Le chlorure d'ammonium peut favoriser la synthèse de la glutamine, ce qui profite indirectement aux protéines riches en glutamine. | ||||||
Azaserine | 115-02-6 | sc-29063 sc-29063A | 50 mg 250 mg | $306.00 $906.00 | 15 | |
L'azasérine peut augmenter la demande cellulaire en glutamine, activant potentiellement des voies connexes. | ||||||
Acivicin | 42228-92-2 | sc-200498B sc-200498C sc-200498 sc-200498D | 1 mg 5 mg 10 mg 25 mg | $102.00 $408.00 $642.00 $1275.00 | 10 | |
L'acicvicine inhibe l'utilisation de la glutamine, affectant indirectement l'activité des protéines riches en glutamine. | ||||||
CB 839 | 1439399-58-2 | sc-507354 | 10 mg | $140.00 | ||
Le CB-839 inhibe sélectivement la glutaminase, ce qui a un impact sur le métabolisme de la glutamine et les protéines associées. | ||||||
6-Thioguanine | 154-42-7 | sc-205587 sc-205587A | 250 mg 500 mg | $41.00 $53.00 | 3 | |
Le phénylbutyrate peut moduler les niveaux de glutamine, affectant indirectement les protéines ayant des domaines riches en glutamine. | ||||||