Date published: 2026-5-7

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FCM Lysing solution (1x)

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For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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FCM Lysing Solution (1x) is a reagent primarily used in flow cytometry, a powerful technique employed in cell biology and immunology research. Its main function is to lyse red blood cells (RBCs) in blood samples while preserving leukocytes for subsequent analysis. The mechanism of action involves the disruption of RBC membranes, leading to their rupture and release of intracellular contents, while leaving leukocytes intact. This allows for accurate and reliable analysis of leukocyte populations, including lymphocytes, monocytes, and granulocytes, based on their surface markers and intracellular components. FCM Lysing Solution (1x) has been extensively used in various research applications, including immunophenotyping, cell cycle analysis, apoptosis assays, and stem cell research. Researchers utilize this reagent to characterize immune cell populations, investigate disease pathology, monitor treatment responses, and study cellular processes underlying normal physiology and pathology. Additionally, FCM Lysing Solution (1x) is essential for the development and validation of new flow cytometry protocols and assays, contributing to the advancement of basic and translational research in immunology, hematology, oncology, and beyond. Its efficacy, reliability, and compatibility with different sample types make it a fundamental tool for flow cytometry-based studies aiming to unravel the complexities of the immune system and cellular biology.


FCM Lysing solution (1x) References

  1. Effects of ropivacaine on adhesion molecule CD11b expression and function in human neutrophils.  |  Zhu, X., et al. 2010. Int Immunopharmacol. 10: 662-7. PMID: 20348036
  2. Novel immunotherapy for metastatic bladder cancer using vaccine of human interleukin-2 surface-modified MB 49 cells.  |  Zhang, X., et al. 2011. Urology. 78: 722.e1-722.e6. PMID: 21741685
  3. Sequential administration of GM-CSF and IL-2 surface-modified MB49 cells vaccines against the metastatic bladder cancer.  |  Shi, X., et al. 2013. Urol Oncol. 31: 883-93. PMID: 21924648
  4. FTY720 and cyclosporin protect ovarian tissue grafted into rabbits.  |  Ying, Y., et al. 2013. Eur J Obstet Gynecol Reprod Biol. 171: 88-95. PMID: 24035595
  5. Evaluation of toxicity and adjuvant effects of peptidoglycan microspheres orally administered to mice.  |  Sun, Q., et al. 2015. J Microencapsul. 32: 46-53. PMID: 25090591
  6. PD-1/PD-L1 blockade enhances the efficacy of SA-GM-CSF surface-modified tumor vaccine in prostate cancer.  |  Shi, X., et al. 2017. Cancer Lett. 406: 27-35. PMID: 28797844
  7. PD-1 blockade enhances the antitumor efficacy of GM-CSF surface-modified bladder cancer stem cells vaccine.  |  Shi, X., et al. 2018. Int J Cancer. 142: 2106-2117. PMID: 29243219
  8. 3-Dehydroandrographolide protects against lipopolysaccharide-induced inflammation through the cholinergic anti-inflammatory pathway.  |  Lu, Z., et al. 2018. Biochem Pharmacol. 158: 305-317. PMID: 30391477
  9. [Role of erythroblast-like Ter cells in the pathogenesis of collagen-induced arthritis].  |  Wang, P., et al. 2019. Beijing Da Xue Xue Bao Yi Xue Ban. 51: 445-450. PMID: 31209415
  10. Increased Tim-3 expression on TILs during treatment with the Anchored GM-CSF vaccine and anti-PD-1 antibodies is inversely correlated with response in prostate cancer.  |  Zhang, X., et al. 2020. J Cancer. 11: 648-656. PMID: 31942188
  11. Puerarin Increases Survival and Protects Against Organ Injury by Suppressing NF-κB/JNK Signaling in Experimental Sepsis.  |  Wang, L., et al. 2020. Front Pharmacol. 11: 560. PMID: 32457606
  12. Alteration of immune profiles is associated with pulmonary function and symptoms in patients with chronic obstructive pulmonary disease.  |  Li, S., et al. 2021. Mol Med Rep. 24: PMID: 34435653
  13. Baicalein suppresses lipopolysaccharide-induced acute lung injury by regulating Drp1-dependent mitochondrial fission of macrophages.  |  Jiang, C., et al. 2022. Biomed Pharmacother. 145: 112408. PMID: 34801855

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

FCM Lysing solution (1x), 150 ml

sc-3621
150 ml
$62.00

what is FCM?

Asked by: Ashiq
Thank you for your question. FCM is an abbreviation for the research application of Flow Cytometry.
Answered by: Technical Support
Date published: 2025-08-11
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Rated 5 out of 5 by from Works really well!I bought this solution for the lysis of cells in adipose tissues and it works really well!
Date published: 2016-12-22
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FCM Lysing solution (1x) is rated 5.0 out of 5 by 1.
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