Date published: 2026-4-25

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SIRP-α Antibodies

Santa Cruz Biotechnology offers a broad range of SIRP-α monoclonal antibodies for research focused on understanding Signal Regulatory Protein Alpha (SIRP-α). Multiple applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SIRP-α plays a critical role in regulating immune responses by mediating interactions between immune cells and their environment. Signal Regulatory Protein Alpha is involved in the inhibition of phagocytosis and the modulation of T cell activation, making it a key player in maintaining immune homeostasis. Understanding SIRP-α function is essential for developing therapeutic strategies in various diseases, including cancer and autoimmune disorders. Signal Regulatory Protein Alpha research continues to reveal new insights into immune system regulation and cellular signaling pathways. Ongoing studies of SIRP-α contribute to our understanding of immune cell interactions and their implications in disease progression. Research utilizing SIRP-α monoclonal antibodies from Santa Cruz Biotechnology enables scientists worldwide to advance our understanding of immune system regulation and potential therapeutic applications.

SEE ALSO...

SIRP-α Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SIRP-α Antibody (SE7C2)

sc-23863mouse IgG1 κ(h)WB, IP, FCMh
13
(7)

SIRP-α Antibody (C-7)

sc-376884mouse IgG2a κ475-503 (h)WB, IP, IF, IHC(P), ELISAm, r, h
5
(5)

SIRP-α Antibody (OX41)

sc-53115mouse IgG2a κ(r)WB, IP, IF, IHC(P), FCMm, r

new

(1)

SIRP-α/β Antibody (A-1)

sc-17803mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAh
3
(6)

SIRP-α/β Antibody (148)

sc-53605mouse IgG1 κFL (h)WB, IP, FCMh

new

(1)

SIRP-α/β1 Antibody (E-7)

sc-55491mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAh

new

(2)

SIRP-α/β1 Antibody (C-8)

sc-373896mouse IgG1 κ22-53 (h)WB, IP, IF, ELISAh
1
(1)

SIRP-α/β1 Antibody (A-1)

sc-376220mouse IgG2b κ22-53 (h)WB, IP, IF, ELISAh

new

(2)

SIRP-α CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIRP-α CRISPR/Cas9 KO Plasmid (h)

sc-401201hGene KnockoutGFP0
(0)

SIRP-α CRISPR/Cas9 KO Plasmid (m)

sc-422514mGene KnockoutGFP0
(0)

SIRP-α HDR Plasmid (m)

sc-422514-HDRmHomology Directed RepairPuromycin0
(0)

SIRP-α Double Nickase Plasmid (m)

sc-422514-NICmGene KnockoutPuromycin0
(0)

SIRP-α Double Nickase Plasmid (m2)

sc-422514-NIC-2mGene KnockoutPuromycin0
(0)

SIRP-α siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIRP-α siRNA (h)

sc-44106hGene SilencingN/A
1
(0)

SIRP-α shRNA Plasmid (h)

sc-44106-SHhGene SilencingPuromycin
1
(0)

SIRP-α shRNA (h) Lentiviral Particles

sc-44106-VhGene SilencingPuromycin
1
(0)

SIRP-α siRNA (m)

sc-36493mGene SilencingN/A
3
(0)

SIRP-α siRNA (m2)

sc-40980mGene SilencingN/A0
(0)

SIRP-α shRNA Plasmid (m)

sc-36493-SHmGene SilencingPuromycin
3
(0)

SIRP-α shRNA Plasmid (m2)

sc-40980-SHmGene SilencingPuromycin0
(0)

SIRP-α shRNA (m) Lentiviral Particles

sc-36493-VmGene SilencingPuromycin
3
(0)

SIRP-α shRNA (m2) Lentiviral Particles

sc-40980-VmGene SilencingPuromycin0
(0)

SIRP-α/β/γ siRNA (h)

sc-36492hGene SilencingN/A0
(0)

SIRP-α/β1/γ shRNA Plasmid (h)

sc-36492-SHhGene SilencingPuromycin0
(0)

SIRP-α/β1/γ shRNA (h) Lentiviral Particles

sc-36492-VhGene SilencingPuromycin0
(0)