EID-1, or "EP300 Interacting Inhibitor of Differentiation 1," is a protein that plays a significant role in the regulation of cell differentiation, a fundamental process in which cells develop into their mature forms and functions. EID-1 acts as a modulator of transcription, influencing the expression of genes involved in cell differentiation pathways.This protein functions by interacting with EP300 (E1A binding protein p300), a well-known transcriptional coactivator involved in a variety of cellular processes including proliferation, differentiation, and apoptosis. EID-1 inhibits the activity of EP300, thereby modulating its role in transcription regulation. Through this interaction, EID-1 indirectly affects the expression of genes that are crucial for the differentiation of cells, particularly in muscle and other tissues.
EID-1's inhibition of EP300 is particularly notable in the context of myogenesis, the process of muscle cell formation. It has been observed to play a role in inhibiting muscle differentiation by interfering with the transcriptional activity necessary for muscle cell development. This inhibition is crucial in maintaining a balance between cell proliferation and differentiation during muscle formation.The regulatory role of EID-1 extends to other cell types and tissues as well, suggesting its broader significance in the process of cellular differentiation. The interaction between EID-1 and EP300 and their subsequent impact on gene expression is a subject of ongoing research, especially in understanding the molecular mechanisms underlying various differentiation processes.
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| Nombre del producto | NÚMERO DE CAS # | Número de catálogo | Cantidad | Precio | MENCIONES | Clasificación |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Inhibidor de la histona deacetilasa (HDAC), que puede influir indirectamente en la actividad de EID-1 alterando la estructura de la cromatina y la expresión génica. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Un inhibidor de la ADN metiltransferasa, que puede afectar a la actividad de la EID-1 alterando la metilación del ADN y los patrones de expresión génica. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Otro inhibidor de HDAC, que podría influir indirectamente en EID-1 al afectar a la remodelación de la cromatina y la expresión génica. | ||||||
RGFP966 | 1357389-11-7 | sc-507300 | 5 mg | $115.00 | ||
Un inhibidor selectivo de HDAC3, que puede afectar a la actividad de EID-1 a través de cambios en la expresión génica y la estructura de la cromatina. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Un inhibiteur d'HDAC bien connu, qui pourrait avoir un effet indirect sur l'EID-1 par le biais de modifications épigénétiques. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
Un inhibidor selectivo de HDAC, que podría influir en la actividad de EID-1 modulando la expresión génica. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Un inhibidor de HDAC, que potencialmente afecta a la actividad de EID-1 a través de cambios epigenéticos y la expresión génica. | ||||||
Mocetinostat | 726169-73-9 | sc-364539 sc-364539B sc-364539A | 5 mg 10 mg 50 mg | $214.00 $247.00 $1463.00 | 2 | |
Un inhibidor selectivo de HDAC, potencialmente impactante en EID-1 a través de alteraciones en la cromatina y la expresión génica. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
Un potente inhibidor de la HDAC, que podría influir indirectamente en la EID-1 afectando a la expresión génica y a la estructura de la cromatina. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $218.00 $634.00 | 1 | |
Un inhibidor de HDAC, que puede afectar a la actividad de EID-1 modulando los patrones de expresión génica. | ||||||