Date published: 2025-11-1

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DGCR6L Inhibidores

DDX26B Inhibitors constitute a specific class of chemical compounds designed to selectively impede the activity of the DDX26B enzyme. DDX26B, also known as DEAD-box helicase 26B, belongs to the broader family of DEAD-box helicases, which are involved in RNA metabolism and contribute to various aspects of RNA processing, including transcription, splicing, and translation. The development of inhibitors targeting DDX26B is pivotal for scientific exploration, offering specialized tools to elucidate the molecular functions and regulatory roles associated with this particular helicase. As a member of the DEAD-box helicase family, DDX26B likely plays a role in unwinding RNA secondary structures, facilitating RNA-protein interactions, and modulating the dynamic landscape of cellular RNA processing events.

The synthesis and optimization of DDX26B inhibitors necessitate a thorough understanding of the enzyme's structural features and its interactions within cellular pathways. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of DDX26B and interfere with its normal helicase activities. By utilizing DDX26B inhibitors in experimental settings, researchers can investigate the consequences of enzyme inhibition on RNA processing dynamics, shedding light on the specific substrates and molecular pathways governed by DDX26B. The study of DDX26B inhibitors contributes to the broader comprehension of cellular RNA metabolism, providing insights into the intricate molecular mechanisms that regulate gene expression and RNA-related processes in cells.

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Nombre del productoNÚMERO DE CAS #Número de catálogoCantidadPrecioMENCIONESClasificación

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

La α-manitina inhibe la ARN polimerasa II, obstaculizando la transcripción e impidiendo la síntesis del ARNm de DGCR6L.

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
$40.00
$210.00
$816.00
$65.00
394
(15)

La puromicina induce la terminación prematura de la síntesis proteica, afectando a la traducción y reduciendo los niveles de DGCR6L.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

L'actinomycine C1 se lie à l'ADN et inhibe la transcription, ce qui entraîne une diminution de l'expression du DGCR6L.

Cordycepin

73-03-0sc-203902
10 mg
$99.00
5
(1)

La cordicepina interfiere en la síntesis de ARNm, afectando a la transcripción y contribuyendo a la regulación a la baja de DGCR6L.

Flavopiridol Hydrochloride

131740-09-5sc-207687
10 mg
$311.00
(2)

El flavopiridol es un inhibidor de la cinasa dependiente de ciclina que impide la fosforilación de la ARN polimerasa II e inhibe la transcripción de DGCR6L.

Ellipticine

519-23-3sc-200878
sc-200878A
10 mg
50 mg
$142.00
$558.00
4
(1)

La elipticina se intercala en el ADN, inhibiendo la transcripción y provocando una disminución de la expresión de DGCR6L.

Streptonigrin

3930-19-6sc-500892
sc-500892A
1 mg
5 mg
$102.00
$357.00
1
(1)

La estreptolidigina inhibe la ARN polimerasa bacteriana, afectando indirectamente a la expresión de DGCR6L al interferir en la transcripción.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$68.00
$261.00
8
(1)

El ácido micofenólico inhibe la inosina monofosfato deshidrogenasa, afectando indirectamente a la expresión de DGCR6L al alterar la síntesis de purinas.

Blasticidin S Hydrochloride

3513-03-9sc-204655A
sc-204655
25 mg
100 mg
$360.00
$475.00
20
(2)

La blasticidina S induce la terminación prematura durante la traducción, inhibiendo la síntesis de proteínas y reduciendo los niveles de DGCR6L.