Jun Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a synthetic small molecule inhibitor that selectively targets the JUN N-terminal kinase (JNK), which is an upstream activator of JUN. By inhibiting JNK, SP600125 effectively blocks JUN-mediated AP-1 signaling and has been studied for its potential therapeutic applications in cancer and inflammatory diseases. | ||||||
SR 11302 | 160162-42-5 | sc-204295 | 10 mg | $357.00 | 28 | |
SR11302 is a synthetic compound that specifically inhibits the DNA-binding activity of JUN. It prevents the formation of functional JUN-DNA complexes, leading to the suppression of AP-1 signaling. SR11302 has been investigated for its potential as an anticancer agent. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a natural polyphenol compound found in turmeric. It has been reported to inhibit JUN activity and disrupt AP-1 signaling in various cell types. Curcumin's anti-inflammatory and anticancer properties have been attributed, in part, to its ability to modulate JUN and AP-1 activity. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin is a natural compound found in certain bacteria. It inhibits JUN phosphorylation and subsequent activation by blocking protein synthesis. By preventing JUN-mediated AP-1 signaling, anisomycin has been investigated for its potential in cancer therapy and neurodegenerative diseases. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $81.00 $306.00 | 32 | |
Parthenolide is a natural compound found in the plant feverfew (Tanacetum parthenium). It inhibits JUN activation by targeting the inhibitor of κB kinase (IKK), a key regulator of AP-1 signaling. Parthenolide has shown anti-inflammatory and anticancer effects by disrupting JUN-mediated AP-1 activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid compound found in various fruits, vegetables, and herbs. It has been reported to inhibit JUN phosphorylation and subsequent AP-1 signaling in cancer cells. Quercetin's antioxidant and anti-inflammatory properties are partly attributed to its ability to modulate JUN activity. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide is a diterpenoid compound found in the Chinese herb Tripterygium wilfordii. It has been shown to inhibit JUN activation and disrupt AP-1 signaling in cancer cells. Triptolide has been investigated for its potential therapeutic applications in cancer and autoimmune diseases. | ||||||