Date published: 2026-5-25

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CLIC Antibodies

Santa Cruz Biotechnology features a diverse variety of CLIC Antibodies for advanced research in cellular and molecular biology. CLIC Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CLIC proteins, or Chloride Intracellular Channels, play a crucial role in maintaining cellular ion homeostasis and regulating cell volume. CLIC proteins are involved in various physiological processes, including cell signaling, apoptosis, and membrane trafficking. Understanding CLIC protein function is significant for research into numerous diseases, including cancer and neurological disorders. Research focused on CLIC proteins continues to reveal potential therapeutic targets and biomarkers. Investigating CLIC protein expression patterns helps scientists understand their role in cellular processes and disease progression. CLIC monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific understanding of cellular mechanisms and disease pathways.

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CLIC Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CLIC1 Antibody (F-9)

sc-374202mouse IgG2b κ194-241 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(5)

CLIC1 Antibody (356.1)

sc-81873mouse IgG2a κ1-242 (h)WB, IP, IF, IHC(P), ELISAm, r, h
22
(8)

CLIC1 Antibody (B-5)

sc-271051mouse IgG1 κ52-81 (h)WB, IP, IF, ELISAm, r, h
1
(1)

CLIC3 Antibody (D-11)

sc-390006mouse IgG2b κ41-79 (h)WB, IP, IF, ELISAm, r, h
2
(4)

CLIC3 Antibody (405)

sc-81872mouse IgG2a κ137-237 (h)WB, IP, IF, IHC(P), ELISAh
1
(3)

CLIC4 Antibody (45.42)

sc-135739mouse IgG1 κ238-250 (h)WB, IP, IF, IHC(P), ELISAm, r, h
13
(8)

CLIC4/5/6 Antibody (A-11)

sc-271863mouse IgG2a κ181-250 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(5)

CLIC4/5/6 Antibody (F-12)

sc-365133mouse IgG1 κ181-250 (h)WB, IP, IF, ELISAm, r, h

new

(2)

CLIC5B Antibody (D-10)

sc-514066mouse IgG1 κ30-54 (h)WB, IP, IF, ELISAh

new

(1)

CLIC6 Antibody (E-11)

sc-365303mouse IgG2a κ163-195 (m)WB, IP, IF, ELISAm, r
1
(2)

CLIC6 Antibody (C-3)

sc-515339mouse IgG3 κ327-351 (m)WB, IP, IF, ELISAm

new

(0)

CLIC6 Antibody (H-5)

sc-365079mouse IgG1 κ163-195 (m)WB, IP, IF, ELISAm, r

new

(2)

CLIC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CLIC1 CRISPR/Cas9 KO Plasmid (h)

sc-402391hGene KnockoutGFP0
(0)

CLIC1 HDR Plasmid (h)

sc-402391-HDRhHomology Directed RepairPuromycin0
(0)

CLIC1 Double Nickase Plasmid (h)

sc-402391-NIChGene KnockoutPuromycin0
(0)

CLIC1 Double Nickase Plasmid (h2)

sc-402391-NIC-2hGene KnockoutPuromycin0
(0)

CLIC2 CRISPR/Cas9 KO Plasmid (h)

sc-409129hGene KnockoutGFP0
(0)

CLIC2 HDR Plasmid (h)

sc-409129-HDRhHomology Directed RepairPuromycin0
(0)

CLIC2 Double Nickase Plasmid (h)

sc-409129-NIChGene KnockoutPuromycin0
(0)

CLIC2 Double Nickase Plasmid (h2)

sc-409129-NIC-2hGene KnockoutPuromycin0
(0)

CLIC4 CRISPR/Cas9 KO Plasmid (h)

sc-403188hGene KnockoutGFP0
(0)

CLIC4 HDR Plasmid (h)

sc-403188-HDRhHomology Directed RepairPuromycin0
(0)

CLIC5 CRISPR/Cas9 KO Plasmid (h)

sc-405918hGene KnockoutGFP0
(0)

CLIC5 HDR Plasmid (h)

sc-405918-HDRhHomology Directed RepairPuromycin0
(0)

CLIC5 Double Nickase Plasmid (h)

sc-405918-NIChGene KnockoutPuromycin0
(0)

CLIC5 Double Nickase Plasmid (h2)

sc-405918-NIC-2hGene KnockoutPuromycin0
(0)

CLIC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CLIC2 CRISPR Activation Plasmid (h)

sc-409129-ACThGene ActivationPuro, Blast, Hygro0
(0)

CLIC4 CRISPR Activation Plasmid (h)

sc-403188-ACThGene ActivationPuro, Blast, Hygro0
(0)

CLIC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CLIC1 siRNA (h)

sc-60400hGene SilencingN/A
5
(0)

CLIC1 shRNA Plasmid (h)

sc-60400-SHhGene SilencingPuromycin
5
(0)

CLIC1 shRNA (h) Lentiviral Particles

sc-60400-VhGene SilencingPuromycin
5
(0)

CLIC1 siRNA (m)

sc-60401mGene SilencingN/A0
(0)

CLIC1 shRNA Plasmid (m)

sc-60401-SHmGene SilencingPuromycin0
(0)

CLIC1 shRNA (m) Lentiviral Particles

sc-60401-VmGene SilencingPuromycin0
(0)

CLIC2 siRNA (h)

sc-60402hGene SilencingN/A0
(0)

CLIC2 shRNA Plasmid (h)

sc-60402-SHhGene SilencingPuromycin0
(0)

CLIC2 shRNA (h) Lentiviral Particles

sc-60402-VhGene SilencingPuromycin0
(0)

CLIC3 siRNA (h)

sc-62126hGene SilencingN/A0
(0)

CLIC3 shRNA Plasmid (h)

sc-62126-SHhGene SilencingPuromycin0
(0)

CLIC3 shRNA (h) Lentiviral Particles

sc-62126-VhGene SilencingPuromycin0
(0)

CLIC3 siRNA (m)

sc-62127mGene SilencingN/A0
(0)

CLIC3 shRNA Plasmid (m)

sc-62127-SHmGene SilencingPuromycin0
(0)

CLIC3 shRNA (m) Lentiviral Particles

sc-62127-VmGene SilencingPuromycin0
(0)

CLIC4 siRNA (h)

sc-105213hGene SilencingN/A
3
(0)

CLIC4 shRNA Plasmid (h)

sc-105213-SHhGene SilencingPuromycin
3
(0)

CLIC4 shRNA (h) Lentiviral Particles

sc-105213-VhGene SilencingPuromycin
3
(0)

CLIC4 siRNA (m)

sc-142391mGene SilencingN/A0
(0)

CLIC4 shRNA Plasmid (m)

sc-142391-SHmGene SilencingPuromycin0
(0)

CLIC4 shRNA (m) Lentiviral Particles

sc-142391-VmGene SilencingPuromycin0
(0)

CLIC5 siRNA (h)

sc-62128hGene SilencingN/A0
(0)

CLIC5 shRNA Plasmid (h)

sc-62128-SHhGene SilencingPuromycin0
(0)

CLIC5 shRNA (h) Lentiviral Particles

sc-62128-VhGene SilencingPuromycin0
(0)

CLIC5 siRNA (m)

sc-62129mGene SilencingN/A0
(0)

CLIC5 shRNA Plasmid (m)

sc-62129-SHmGene SilencingPuromycin0
(0)

CLIC5 shRNA (m) Lentiviral Particles

sc-62129-VmGene SilencingPuromycin0
(0)

CLIC6 siRNA (h)

sc-62130hGene SilencingN/A0
(0)

CLIC6 shRNA Plasmid (h)

sc-62130-SHhGene SilencingPuromycin0
(0)

CLIC6 shRNA (h) Lentiviral Particles

sc-62130-VhGene SilencingPuromycin0
(0)

CLIC6 siRNA (m)

sc-62131mGene SilencingN/A0
(0)

CLIC6 shRNA Plasmid (m)

sc-62131-SHmGene SilencingPuromycin0
(0)

CLIC6 shRNA (m) Lentiviral Particles

sc-62131-VmGene SilencingPuromycin0
(0)