Date published: 2025-10-7

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GFR α Antibodies

Santa Cruz Biotechnology features a diverse variety of GFR α Antibodies for understanding the role of glial cell line-derived neurotrophic factor (GDNF) family receptor alpha. GFR α Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GFR α proteins mediate the effects of GDNF, which is essential for the survival and maintenance of specific neuronal populations. Research has shown that GFR α plays a significant role in neuroprotection, neuronal differentiation, and the development of the nervous system. Understanding GFR α function opens new possibilities for exploring therapeutic strategies in neurodegenerative diseases and neurological disorders. Current studies indicate that GFR α signaling pathways are involved in multiple aspects of neural development and maintenance. Investigating GFR α mechanisms provides insights into potential therapeutic approaches for various neurological conditions. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing neurobiology knowledge and developing innovative therapeutic strategies.

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GFR α Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GFRα-1 Antibody (E-11)

sc-271546mouse IgG1 κ368-437 (h)WB, IP, IF, IHC(P), ELISAm, r, h
33
(7)

GFRα-3 Antibody (C-3)

sc-398618mouse IgG2b κ33-59 (m)WB, IP, IF, ELISAm, r, h
2
(1)

GFRα-3 Antibody (G-3)

sc-393563mouse IgG1 κ333-368 (m)WB, IP, IF, ELISAm, r, h

new

(1)

GFRα-3 Antibody (J135)

sc-74047mouse IgG1C-Terminal (h)WB, IPh

new

(1)

GFR α CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GFRαL CRISPR/Cas9 KO Plasmid (h)

sc-415831hGene KnockoutGFP0
(0)

GFRαL Double Nickase Plasmid (h)

sc-415831-NIChGene KnockoutPuromycin0
(0)

GFRαL Double Nickase Plasmid (h2)

sc-415831-NIC-2hGene KnockoutPuromycin0
(0)

GFRαL CRISPR/Cas9 KO Plasmid (m)

sc-436523mGene KnockoutGFP0
(0)

GFRαL HDR Plasmid (m)

sc-436523-HDRmHomology Directed RepairPuromycin0
(0)

GFRαL Double Nickase Plasmid (m)

sc-436523-NICmGene KnockoutPuromycin0
(0)

GFRαL Double Nickase Plasmid (m2)

sc-436523-NIC-2mGene KnockoutPuromycin0
(0)

GFRα-1 CRISPR/Cas9 KO Plasmid (h)

sc-401126hGene KnockoutGFP0
(0)

GFRα-1 HDR Plasmid (h)

sc-401126-HDRhHomology Directed RepairPuromycin0
(0)

GFRα-1 Double Nickase Plasmid (h)

sc-401126-NIChGene KnockoutPuromycin0
(0)

GFRα-1 Double Nickase Plasmid (h2)

sc-401126-NIC-2hGene KnockoutPuromycin0
(0)

GFRα-1 CRISPR/Cas9 KO Plasmid (m)

sc-420539mGene KnockoutGFP0
(0)

GFRα-1 HDR Plasmid (m)

sc-420539-HDRmHomology Directed RepairPuromycin0
(0)

GFRα-1 Double Nickase Plasmid (m)

sc-420539-NICmGene KnockoutPuromycin0
(0)

GFRα-1 Double Nickase Plasmid (m2)

sc-420539-NIC-2mGene KnockoutPuromycin0
(0)

GFRα-2 CRISPR/Cas9 KO Plasmid (h)

sc-404010hGene KnockoutGFP0
(0)

GFRα-2 HDR Plasmid (h)

sc-404010-HDRhHomology Directed RepairPuromycin0
(0)

GFRα-2 Double Nickase Plasmid (h)

sc-404010-NIChGene KnockoutPuromycin0
(0)

GFRα-2 Double Nickase Plasmid (h2)

sc-404010-NIC-2hGene KnockoutPuromycin0
(0)

GFRα-2 CRISPR/Cas9 KO Plasmid (m)

sc-420540mGene KnockoutGFP0
(0)

GFRα-2 HDR Plasmid (m)

sc-420540-HDRmHomology Directed RepairPuromycin0
(0)

GFRα-2 Double Nickase Plasmid (m)

sc-420540-NICmGene KnockoutPuromycin0
(0)

GFRα-2 Double Nickase Plasmid (m2)

sc-420540-NIC-2mGene KnockoutPuromycin0
(0)

GFRα-3 CRISPR/Cas9 KO Plasmid (h)

sc-405061hGene KnockoutGFP0
(0)

GFRα-3 CRISPR/Cas9 KO Plasmid (h2)

sc-405061-KO-2hGene KnockoutGFP0
(0)

GFRα-3 HDR Plasmid (h2)

sc-405061-HDR-2hHomology Directed RepairPuromycin0
(0)

GFRα-3 Double Nickase Plasmid (h)

sc-405061-NIChGene KnockoutPuromycin0
(0)

GFRα-3 Double Nickase Plasmid (h2)

sc-405061-NIC-2hGene KnockoutPuromycin0
(0)

GFRα-3 CRISPR/Cas9 KO Plasmid (m)

sc-420541mGene KnockoutGFP0
(0)

GFRα-3 HDR Plasmid (m)

sc-420541-HDRmHomology Directed RepairPuromycin0
(0)

GFRα-3 Double Nickase Plasmid (m)

sc-420541-NICmGene KnockoutPuromycin0
(0)

GFRα-3 Double Nickase Plasmid (m2)

sc-420541-NIC-2mGene KnockoutPuromycin0
(0)

GFRα-4 CRISPR/Cas9 KO Plasmid (h)

sc-408595hGene KnockoutGFP0
(0)

GFRα-4 HDR Plasmid (h)

sc-408595-HDRhHomology Directed RepairPuromycin0
(0)

GFRα-4 Double Nickase Plasmid (h)

sc-408595-NIChGene KnockoutPuromycin0
(0)

GFRα-4 Double Nickase Plasmid (h2)

sc-408595-NIC-2hGene KnockoutPuromycin0
(0)

GFRα-4 CRISPR/Cas9 KO Plasmid (m)

sc-420542mGene KnockoutGFP0
(0)

GFRα-4 HDR Plasmid (m)

sc-420542-HDRmHomology Directed RepairPuromycin0
(0)

GFRα-4 Double Nickase Plasmid (m)

sc-420542-NICmGene KnockoutPuromycin0
(0)

GFRα-4 Double Nickase Plasmid (m2)

sc-420542-NIC-2mGene KnockoutPuromycin0
(0)

GFR α CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GFRαL CRISPR Activation Plasmid (h)

sc-415831-ACThGene ActivationPuro, Blast, Hygro0
(0)

GFRαL CRISPR Activation Plasmid (h2)

sc-415831-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GFRαL Lentiviral Activation Particles (h)

sc-415831-LAChGene ActivationPuro, Blast, Hygro0
(0)

GFRαL Lentiviral Activation Particles (h2)

sc-415831-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GFRαL CRISPR Activation Plasmid (m)

sc-436523-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GFRαL CRISPR Activation Plasmid (m2)

sc-436523-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GFRαL Lentiviral Activation Particles (m)

sc-436523-LACmGene ActivationPuro, Blast, Hygro0
(0)

GFRαL Lentiviral Activation Particles (m2)

sc-436523-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GFRα-1 CRISPR Activation Plasmid (h)

sc-401126-ACThGene ActivationPuro, Blast, Hygro0
(0)

GFRα-1 CRISPR Activation Plasmid (h2)

sc-401126-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GFRα-1 Lentiviral Activation Particles (h)

sc-401126-LAChGene ActivationPuro, Blast, Hygro0
(0)

GFRα-1 Lentiviral Activation Particles (h2)

sc-401126-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GFRα-1 CRISPR Activation Plasmid (m)

sc-420539-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GFRα-1 CRISPR Activation Plasmid (m2)

sc-420539-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GFRα-1 Lentiviral Activation Particles (m)

sc-420539-LACmGene ActivationPuro, Blast, Hygro0
(0)

GFRα-1 Lentiviral Activation Particles (m2)

sc-420539-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GFRα-2 CRISPR Activation Plasmid (h)

sc-404010-ACThGene ActivationPuro, Blast, Hygro0
(0)

GFRα-2 CRISPR Activation Plasmid (h2)

sc-404010-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GFRα-2 Lentiviral Activation Particles (h)

sc-404010-LAChGene ActivationPuro, Blast, Hygro0
(0)

GFRα-2 Lentiviral Activation Particles (h2)

sc-404010-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GFRα-2 CRISPR Activation Plasmid (m)

sc-420540-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GFRα-2 CRISPR Activation Plasmid (m2)

sc-420540-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GFRα-2 Lentiviral Activation Particles (m)

sc-420540-LACmGene ActivationPuro, Blast, Hygro0
(0)

GFRα-2 Lentiviral Activation Particles (m2)

sc-420540-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GFRα-3 CRISPR Activation Plasmid (h)

sc-405061-ACThGene ActivationPuro, Blast, Hygro0
(0)

GFRα-3 CRISPR Activation Plasmid (h2)

sc-405061-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GFRα-3 Lentiviral Activation Particles (h)

sc-405061-LAChGene ActivationPuro, Blast, Hygro0
(0)

GFRα-3 Lentiviral Activation Particles (h2)

sc-405061-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GFRα-3 CRISPR Activation Plasmid (m)

sc-420541-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GFRα-3 CRISPR Activation Plasmid (m2)

sc-420541-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GFRα-3 Lentiviral Activation Particles (m)

sc-420541-LACmGene ActivationPuro, Blast, Hygro0
(0)

GFRα-3 Lentiviral Activation Particles (m2)

sc-420541-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GFRα-4 CRISPR Activation Plasmid (h)

sc-408595-ACThGene ActivationPuro, Blast, Hygro0
(0)

GFRα-4 CRISPR Activation Plasmid (h2)

sc-408595-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GFRα-4 Lentiviral Activation Particles (h)

sc-408595-LAChGene ActivationPuro, Blast, Hygro0
(0)

GFRα-4 Lentiviral Activation Particles (h2)

sc-408595-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GFRα-4 CRISPR Activation Plasmid (m)

sc-420542-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GFRα-4 CRISPR Activation Plasmid (m2)

sc-420542-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GFRα-4 Lentiviral Activation Particles (m)

sc-420542-LACmGene ActivationPuro, Blast, Hygro0
(0)

GFRα-4 Lentiviral Activation Particles (m2)

sc-420542-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GFR α siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GFRαL siRNA (h)

sc-95432hGene SilencingN/A0
(0)

GFRαL shRNA Plasmid (h)

sc-95432-SHhGene SilencingPuromycin0
(0)

GFRαL shRNA (h) Lentiviral Particles

sc-95432-VhGene SilencingPuromycin0
(0)

GFRαL siRNA (m)

sc-145386mGene SilencingN/A0
(0)

GFRαL shRNA Plasmid (m)

sc-145386-SHmGene SilencingPuromycin0
(0)

GFRαL shRNA (m) Lentiviral Particles

sc-145386-VmGene SilencingPuromycin0
(0)

GFRαL siRNA (r)

sc-270688rGene SilencingN/A0
(1)

GFRαL shRNA Plasmid (r)

sc-270688-SHrGene SilencingPuromycin0
(1)

GFRαL shRNA (r) Lentiviral Particles

sc-270688-VrGene SilencingPuromycin0
(1)

GFRα-1 siRNA (h)

sc-35469hGene SilencingN/A
3
(0)

GFRα-1 shRNA Plasmid (h)

sc-35469-SHhGene SilencingPuromycin
3
(0)

GFRα-1 shRNA (h) Lentiviral Particles

sc-35469-VhGene SilencingPuromycin
3
(0)

GFRα-1 siRNA (m)

sc-35470mGene SilencingN/A
4
(0)

GFRα-1 shRNA Plasmid (m)

sc-35470-SHmGene SilencingPuromycin
4
(0)

GFRα-1 shRNA (m) Lentiviral Particles

sc-35470-VmGene SilencingPuromycin
4
(0)

GFRα-1 siRNA (r)

sc-270400rGene SilencingN/A0
(0)

GFRα-1 shRNA Plasmid (r)

sc-270400-SHrGene SilencingPuromycin0
(0)

GFRα-1 shRNA (r) Lentiviral Particles

sc-270400-VrGene SilencingPuromycin0
(0)

GFRα-2 siRNA (h)

sc-35471hGene SilencingN/A0
(0)

GFRα-2 shRNA Plasmid (h)

sc-35471-SHhGene SilencingPuromycin0
(0)

GFRα-2 shRNA (h) Lentiviral Particles

sc-35471-VhGene SilencingPuromycin0
(0)

GFRα-2 siRNA (m)

sc-35472mGene SilencingN/A0
(0)

GFRα-2 shRNA Plasmid (m)

sc-35472-SHmGene SilencingPuromycin0
(0)

GFRα-2 shRNA (m) Lentiviral Particles

sc-35472-VmGene SilencingPuromycin0
(0)

GFRα-3 siRNA (h)

sc-41972hGene SilencingN/A0
(0)

GFRα-3 shRNA Plasmid (h)

sc-41972-SHhGene SilencingPuromycin0
(0)

GFRα-3 shRNA (h) Lentiviral Particles

sc-41972-VhGene SilencingPuromycin0
(0)

GFRα-3 siRNA (m)

sc-41973mGene SilencingN/A0
(0)

GFRα-3 shRNA Plasmid (m)

sc-41973-SHmGene SilencingPuromycin0
(0)

GFRα-3 shRNA (m) Lentiviral Particles

sc-41973-VmGene SilencingPuromycin0
(0)

GFR-α4 siRNA (h)

sc-60683hGene SilencingN/A0
(0)

GFR-α4 shRNA Plasmid (h)

sc-60683-SHhGene SilencingPuromycin0
(0)

GFR-α4 shRNA (h) Lentiviral Particles

sc-60683-VhGene SilencingPuromycin0
(0)

GFR-α4 siRNA (m)

sc-60684mGene SilencingN/A0
(0)

GFR-α4 shRNA Plasmid (m)

sc-60684-SHmGene SilencingPuromycin0
(0)

GFR-α4 shRNA (m) Lentiviral Particles

sc-60684-VmGene SilencingPuromycin0
(0)