Date published: 2026-4-25

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GFRα-3 Antibody (J135): sc-74047

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Datasheets
  • GFRα-3 Antibody (J135) is a mouse monoclonal IgG1 provided at 100 µg/ml
  • raised against a protein lacking the C-terminal domain of GFRα-3 of human origin
  • recommended for detection of GFRα-3 of human origin by WB and IP
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GFRα-3 Antibody (J135). This work is in progress.
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    GFRα-3 Antibody (J135) is a mouse monoclonal IgG1 antibody that detects GFRα-3 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. GFRα-3 is a member of the glial cell line-derived neurotrophic factor (GDNF) receptor family, which plays a crucial role in neuronal survival and development. Unlike its counterparts, GFRα-1 and GFRα-2, which are involved in mediating GDNF and neurturin signaling, GFRα-3 is primarily expressed during embryonic development, suggesting importance in early neural differentiation and growth. The unique expression pattern of GFRα-3 highlights potential roles in developmental processes and implications in neurodevelopmental disorders. Understanding GFRα-3 function and regulation can provide insights into therapeutic strategies for neurodegenerative diseases, making anti-GFRα-3 antibody (J135) an essential tool for researchers studying neuronal signaling pathways and their impact on human health.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    GFRα-3 Antibody (J135)

    sc-74047
    100 µg/ml
    $322.00

    I am using GFRα-3 (J135): sc-74047 antibody for immunoprecipitation, how much antibody should I use?

    Asked by: AbPolly
    Thank you for your question. We recommend using 1–10 µl (i.e., 0.2–2 µg) of antibody with 1 ml of cell lysate. However, optimal antibody concentration should be determined by titration. Please find our full immunoprecipitation protocol here: https://www.scbt.com/scbt/resources/protocols/immunoprecipitation-western-blots
    Answered by: Technical Support
    Date published: 2017-03-24
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    Rated 3 out of 5 by from Performed well in WB in human GFRPerformed well in WB in human GFR -3 transfected 293T whole cell lysate. -SCBT QC
    Date published: 2014-07-19
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    GFRα-3 Antibody (J135) is rated 3.0 out of 5 by 1.
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