ZNF768 Inhibitors
ZNF768 inhibitors belong to a specific class of chemicals that are designed to modulate the activity of the ZNF768 protein. ZNF768, also known as Zinc finger protein 768, is a transcription factor that plays a role in regulating gene expression. It contains multiple zinc finger domains, which are protein structural motifs involved in DNA binding. ZNF768 inhibitors are designed to specifically target and bind to ZNF768, thereby interfering with its normal function. By binding to the protein, these inhibitors disrupt the interactions between ZNF768 and its target DNA sequences.
The development of ZNF768 inhibitors involves a combination of computational modeling, and biological screening. Researchers identify small molecules or compounds bind to ZNF768 based on their predicted binding affinity and specificity. These candidate inhibitors are then synthesized and tested in laboratory settings to determine their ability to inhibit ZNF768 activity. Overall, ZNF768 inhibitors provide researchers with a means to experimentally manipulate ZNF768 activity and gain insights into the molecular mechanisms underlying its function.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
By targeting RNA polymerase II, α-amanitin could disrupt the transcriptional landscape, potentially hindering ZNF768's role in transcription regulation by this polymerase. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Its intercalation into DNA can prevent transcription initiation and elongation. ZNF768, if directly interacting with transcribing DNA, might see its binding or regulatory capacity impacted. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
By inhibiting CTD phosphorylation of RNA polymerase II, DRB could alter the transcriptional process, potentially affecting ZNF768's interaction or modulation of specific gene transcriptions. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
As it suppresses RNA polymerase II-dependent transcription, ZNF768's RNA binding and regulatory functions might be indirectly affected due to a reduced transcriptional activity. | ||||||
Ivermectin | 70288-86-7 | sc-203609 sc-203609A | 100 mg 1 g | $56.00 $75.00 | 2 | |
Disrupting nuclear localization could impair ZNF768's ability to access nuclear RNA targets, thereby impacting its regulatory functions within the nucleus. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1 functions to disrupt the bromodomain containing proteins, affecting ZNF768's regulatory functions. | ||||||
Isoginkgetin | 548-19-6 | sc-507430 | 5 mg | $225.00 | ||
By inhibiting spliceosome assembly, RNA processing might be affected, potentially altering the pool or structure of RNA molecules that ZNF768 interacts with. | ||||||
Pladienolide B | 445493-23-2 | sc-391691 sc-391691B sc-391691A sc-391691C sc-391691D sc-391691E | 0.5 mg 10 mg 20 mg 50 mg 100 mg 5 mg | $290.00 $5572.00 $10815.00 $25000.00 $65000.00 $2781.00 | 63 | |
Interfering with spliceosome function might impact ZNF768's RNA targets, if it is involved in recognizing or regulating spliced RNA forms. | ||||||
Spliceostatin A | 391611-36-2 | sc-507481 | 1 mg | $1800.00 | ||
Similar to other spliceosome inhibitors, it could modulate the RNA landscape within the nucleus, possibly altering ZNF768's interaction profile with RNAs. | ||||||