ZMYND17 Inhibitors
ZMYND17 inhibitors mainly comprise compounds that have an effect on chromatin remodeling, histone modification, or transcription regulation. SAHA and Trichostatin A, for instance, are histone deacetylase (HDAC) inhibitors. Their primary function is to the deacetylation of histones, which in turn can result in a more open chromatin state, influencing the functions or interactions of proteins like ZMYND17 that may be associated with chromatin.
On the other hand, compounds such as 5-Aza-2'-deoxycytidine, a DNA methyltransferase inhibitor, shed light on the DNA methylation perspective. Changes in DNA methylation states can influence gene expression and chromatin accessibility, and proteins associated with chromatin, including ZMYND17, may see a change in their activity or interaction profiles. The BET bromodomain inhibitors like JQ1 and I-BET151 bring into focus the bromodomain protein's role in recognizing acetylated lysine residues on histone tails, essential for transcription regulation. Inhibition of these proteins can lead to altered transcriptional landscapes, possibly influencing the activity or interactions of ZMYND17.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Histone deacetylase inhibitor that can influence chromatin remodeling and may affect proteins associated with ZMYND17. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Another histone deacetylase inhibitor which can alter chromatin state and potentially influence ZMYND17 activity. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor, influencing DNA methylation and possibly affecting ZMYND17's associated pathways. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
BET bromodomain inhibitor that affects transcription regulation and may have indirect effects on ZMYND17 function. | ||||||
RGFP966 | 1357389-11-7 | sc-507300 | 5 mg | $115.00 | ||
HDAC3-specific inhibitor that affects gene expression and chromatin remodeling, potentially influencing ZMYND17. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
BET bromodomain inhibitor, which can alter transcriptional programs and potentially affect ZMYND17's associated functions. | ||||||
UNC1999 | 1431612-23-5 | sc-475314 | 5 mg | $142.00 | 1 | |
An inhibitor of EZH2 and EZH1, affecting methylation states and possibly interacting with pathways associated with ZMYND17. | ||||||
GSK126 | 1346574-57-9 | sc-490133 sc-490133A sc-490133B | 1 mg 5 mg 10 mg | $92.00 $243.00 $306.00 | ||
EZH2 methyltransferase inhibitor that affects chromatin marks and may indirectly influence ZMYND17 activity. | ||||||
PFI-1 | 1403764-72-6 | sc-478504 | 5 mg | $98.00 | ||
BET bromodomain inhibitor that affects gene expression and may indirectly affect ZMYND17. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
HDAC inhibitor that modulates gene expression and may influence pathways associated with ZMYND17. | ||||||