Zearalenone Activators
The term Zearalenone Activators refers to a group of chemical compounds that have garnered attention in the field of food safety and agricultural research due to their potential to influence the metabolism and detoxification of zearalenone (ZEN), a mycotoxin produced by various strains of Fusarium fungi. ZEN is a naturally occurring compound that can contaminate crops like maize, wheat, barley, and oats, posing a significant health risk to humans and animals when consumed. ZEN is particularly concerning because of its estrogenic properties, which can disrupt endocrine systems and have adverse effects on reproductive health.
These Zearalenone Activators are characterized by their ability to modulate the enzymatic pathways involved in the detoxification and metabolism of ZEN within living organisms, such as humans, animals, or even plants. Some of the compounds in this class are naturally occurring phytochemicals found in various foods, while others are synthetic or semi-synthetic derivatives. Their commonality lies in their capacity to activate specific enzymes, such as cytochrome P450s and glutathione S-transferases, which play pivotal roles in the biotransformation and elimination of ZEN from the body. By activating these enzymes, Zearalenone Activators may enhance the rate at which ZEN is metabolized and subsequently excreted, reducing the duration and intensity of ZEN's toxic effects.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
I3C is a natural compound found in cruciferous vegetables like broccoli and cabbage. It has been studied for its potential to induce detoxifying enzymes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Found in red grapes and wine, resveratrol has been investigated for its ability to activate enzymes that help metabolize and eliminate ZEN. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid present in various fruits and vegetables, quercetin has antioxidant properties and may stimulate enzymes involved in ZEN detoxification. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
This compound, found in turmeric, may help induce enzymes that mitigate the effects of ZEN. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a polyphenol found in green tea and has been studied for its potential to activate detoxifying enzymes against ZEN. | ||||||
Silymarin group, mixture of isomers | 65666-07-1 | sc-301806 | 50 g | $325.00 | ||
Found in milk thistle, silymarin is known for its liver-protective properties and may support the liver in detoxifying ZEN. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
This essential mineral is a cofactor for several enzymes involved in detoxification processes. Adequate selenium intake may enhance the body's ability to metabolize ZEN. | ||||||
DL-α-Tocopherol | 10191-41-0 | sc-294383 sc-294383A sc-294383B sc-294383C | 5 g 25 g 100 g 500 g | $26.00 $52.00 $124.00 $326.00 | 3 | |
Vitamin E is an antioxidant that may protect against the oxidative stress induced by ZEN exposure. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A phytoestrogen found in soybeans, genistein may modulate estrogen receptor activity and reduce the estrogenic effects of ZEN. | ||||||
Chrysin | 480-40-0 | sc-204686 | 1 g | $38.00 | 13 | |
This natural flavonoid, found in honey and propolis, has been investigated for its potential to inhibit the estrogenic activity of ZEN and support detoxification processes. | ||||||