Date published: 2026-4-1

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ZC3H12B Activators

ZC3H12B Activators belong to a chemical class designed to modulate the activity of the ZC3H12B protein, also known as Regnase-2. ZC3H12B is an endoribonuclease enzyme that plays a crucial role in post-transcriptional regulation of gene expression. It is a member of the CCCH zinc finger protein family and is primarily involved in the degradation of specific messenger RNAs (mRNAs) in immune cells. The activation of ZC3H12B through these activators can have significant implications for understanding how the immune system controls gene expression to maintain homeostasis and respond to various external stimuli.

ZC3H12B Activators are valuable tools in scientific research aimed at unraveling the complex regulatory mechanisms governing immune responses and inflammation. By modulating ZC3H12B's activity, researchers can investigate how this protein selectively targets and degrades specific mRNAs, thereby influencing the expression of key immune-related genes. This can provide insights into the molecular basis of autoimmune diseases, inflammatory disorders, and other immune-related conditions. Overall, ZC3H12B Activators are essential for advancing our knowledge of immune system functioning and its role in health and disease.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Lipopolysaccharide, E. coli O55:B5

93572-42-0sc-221855
sc-221855A
sc-221855B
sc-221855C
10 mg
25 mg
100 mg
500 mg
$98.00
$171.00
$425.00
$1560.00
12
(2)

LPS, a component of bacterial cell walls, might stimulate ZC3H12B expression in immune cells during bacterial infections.

Thymosin β4

77591-33-4sc-396076
sc-396076A
1 mg
100 mg
$134.00
$7140.00
(0)

TGF-β, involved in cell growth and differentiation, could regulate ZC3H12B in tissue repair and fibrosis.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic Acid, a derivative of Vitamin A, might influence ZC3H12B expression during cell differentiation and immune modulation.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Glucocorticoids could affect ZC3H12B expression as part of their broad anti-inflammatory and immunomodulatory effects.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Vitamin D3 may modulate ZC3H12B expression, particularly in immune cells, due to its role in immune regulation.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin, which elevates cAMP levels, could impact ZC3H12B expression through cAMP-mediated signaling pathways.

Hydrogen Peroxide

7722-84-1sc-203336
sc-203336A
sc-203336B
100 ml
500 ml
3.8 L
$31.00
$61.00
$95.00
28
(1)

As an oxidative stress agent, hydrogen peroxide might induce ZC3H12B expression in response to cellular stress.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin, with its anti-inflammatory properties, might modulate ZC3H12B expression in various cell types.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Nrf2 activators, known for their role in oxidative stress response, could influence ZC3H12B expression in response to oxidative stress.