ZC3H12B Activators belong to a chemical class designed to modulate the activity of the ZC3H12B protein, also known as Regnase-2. ZC3H12B is an endoribonuclease enzyme that plays a crucial role in post-transcriptional regulation of gene expression. It is a member of the CCCH zinc finger protein family and is primarily involved in the degradation of specific messenger RNAs (mRNAs) in immune cells. The activation of ZC3H12B through these activators can have significant implications for understanding how the immune system controls gene expression to maintain homeostasis and respond to various external stimuli.
ZC3H12B Activators are valuable tools in scientific research aimed at unraveling the complex regulatory mechanisms governing immune responses and inflammation. By modulating ZC3H12B's activity, researchers can investigate how this protein selectively targets and degrades specific mRNAs, thereby influencing the expression of key immune-related genes. This can provide insights into the molecular basis of autoimmune diseases, inflammatory disorders, and other immune-related conditions. Overall, ZC3H12B Activators are essential for advancing our knowledge of immune system functioning and its role in health and disease.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
LPS, a component of bacterial cell walls, might stimulate ZC3H12B expression in immune cells during bacterial infections. | ||||||
Thymosin β4 | 77591-33-4 | sc-396076 sc-396076A | 1 mg 100 mg | $134.00 $7140.00 | ||
TGF-β, involved in cell growth and differentiation, could regulate ZC3H12B in tissue repair and fibrosis. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid, a derivative of Vitamin A, might influence ZC3H12B expression during cell differentiation and immune modulation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Glucocorticoids could affect ZC3H12B expression as part of their broad anti-inflammatory and immunomodulatory effects. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 may modulate ZC3H12B expression, particularly in immune cells, due to its role in immune regulation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin, which elevates cAMP levels, could impact ZC3H12B expression through cAMP-mediated signaling pathways. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
As an oxidative stress agent, hydrogen peroxide might induce ZC3H12B expression in response to cellular stress. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, with its anti-inflammatory properties, might modulate ZC3H12B expression in various cell types. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Nrf2 activators, known for their role in oxidative stress response, could influence ZC3H12B expression in response to oxidative stress. | ||||||