Date published: 2025-10-21

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ZAP-70 Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of ZAP-70 monoclonal antibodies for immunology and cell signaling research. ZAP-70 monoclonal antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). ZAP-70, or Zeta-chain-associated protein kinase 70, plays a central role in T-cell receptor signaling and is essential for T-cell activation and proliferation. The protein's function is crucial in the immune response, making ZAP-70 an important marker in the study of T-cell malignancies and autoimmune diseases. Research focused on ZAP-70 can reveal potential therapeutic targets for various immunological disorders. Scientists can explore the complex mechanisms of T-cell signaling pathways using ZAP-70 monoclonal antibodies. Understanding the molecular interactions of ZAP-70 helps advance knowledge about immune system regulation and dysfunction. Investigating ZAP-70's involvement in different cellular processes contributes to developing new therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of immune system function and disease mechanisms.

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ZAP-70 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

ZAP-70 Antibody (1E7.2)

sc-32760mouse IgG1 κ282-307 (h)WB, IP, IF, FCMm, r, h
31
(9)

ZAP-70 Antibody (G-4)

sc-17760mouse IgG1 κ253-304 (h)WB, IP, IF, FCM, ELISAh
2
(6)

ZAP-70 Antibody (4H386)

sc-73279mouse IgG1 κ282-307 (h)WB, IP, IF, FCMm, r, h
1
(1)

ZAP-70 Antibody (3D2A4)

sc-53899mouse IgG2a κ(h)WB, IP, IFm, r, h

new

(2)

ZAP-70 Antibody (24A)

sc-136126mouse IgG1316-325 (h)WB, IPm, r, h

new

(1)

ZAP-70 Antibody (29)

sc-136305mouse IgG2a468-619 (h)WB, IPm, r, h

new

(1)

ZAP-70 Antibody (A-1)

sc-365490mouse IgG2b κ5-35 (h)WB, IP, IF, ELISAm, r, h
1
(2)

ZAP-70 Antibody (A-8)

sc-374347mouse IgG1 κ5-35 (h)WB, IP, IF, ELISAm, r, h

new

(1)

Phospho-Specific ZAP-70 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-ZAP-70 Antibody (pY319.17A)

sc-136248mouse IgG1 κTyr 319 (h)WB, IPm, r, h
2
(1)

ZAP-70 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Zap-70 CRISPR/Cas9 KO Plasmid (h)

sc-400826hGene KnockoutGFP0
(0)

Zap-70 CRISPR/Cas9 KO Plasmid (h2)

sc-400826-KO-2hGene KnockoutGFP0
(0)

Zap-70 Double Nickase Plasmid (h)

sc-400826-NIChGene KnockoutPuromycin0
(0)

Zap-70 Double Nickase Plasmid (h2)

sc-400826-NIC-2hGene KnockoutPuromycin0
(0)

Zap-70 CRISPR/Cas9 KO Plasmid (m)

sc-423755mGene KnockoutGFP0
(0)

Zap-70 HDR Plasmid (m)

sc-423755-HDRmHomology Directed RepairPuromycin0
(0)

Zap-70 Double Nickase Plasmid (m)

sc-423755-NICmGene KnockoutPuromycin0
(0)

Zap-70 Double Nickase Plasmid (m2)

sc-423755-NIC-2mGene KnockoutPuromycin0
(0)

ZAP-70 CRISPR HDR Plasmid (h2)

sc-400826-HDR-2hHomology Directed RepairPuromycin0
(0)

ZAP-70 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Zap-70 CRISPR Activation Plasmid (h)

sc-400826-ACThGene ActivationPuro, Blast, Hygro0
(0)

Zap-70 CRISPR Activation Plasmid (h2)

sc-400826-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Zap-70 Lentiviral Activation Particles (h)

sc-400826-LAChGene ActivationPuro, Blast, Hygro0
(0)

Zap-70 Lentiviral Activation Particles (h2)

sc-400826-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Zap-70 CRISPR Activation Plasmid (m)

sc-423755-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Zap-70 CRISPR Activation Plasmid (m2)

sc-423755-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Zap-70 Lentiviral Activation Particles (m)

sc-423755-LACmGene ActivationPuro, Blast, Hygro0
(0)

Zap-70 Lentiviral Activation Particles (m2)

sc-423755-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ZAP-70 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ZAP-70 siRNA (h)

sc-29526hGene SilencingN/A
1
(0)

ZAP-70 shRNA Plasmid (h)

sc-29526-SHhGene SilencingPuromycin
1
(0)

ZAP-70 shRNA (h) Lentiviral Particles

sc-29526-VhGene SilencingPuromycin
1
(0)

ZAP-70 siRNA (m)

sc-36867mGene SilencingN/A
1
(0)

ZAP-70 shRNA Plasmid (m)

sc-36867-SHmGene SilencingPuromycin
1
(0)

ZAP-70 shRNA (m) Lentiviral Particles

sc-36867-VmGene SilencingPuromycin
1
(0)