Date published: 2025-12-19

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YTHDF3 Activators

YTHDF3 Activators belong to a distinctive chemical class that exerts its influence at the molecular level, specifically targeting the YTH domain family protein 3 (YTHDF3). YTHDF3 is a member of the YTH domain-containing family of proteins, which are integral players in the dynamic and intricate landscape of RNA metabolism. The YTHDF3 Activators operate by modulating the activity of YTHDF3, a critical component of the mRNA decay machinery. YTHDF3 is known for its involvement in the regulation of mRNA stability and degradation, thereby influencing the abundance of specific transcripts within the cellular environment.

YTHDF3 Activators are characterized by their ability to interact selectively with YTHDF3, often through intricate binding motifs that facilitate precise engagement with the protein's RNA recognition pockets. This interaction subsequently alters the conformation and functional dynamics of YTHDF3, leading to downstream effects on RNA processing and degradation. The nuanced control exerted by YTHDF3 Activators over these cellular processes underscores the importance of understanding the molecular mechanisms governing RNA fate and turnover. Given the pivotal role of YTHDF3 in shaping the cellular transcriptome, the development and exploration of YTHDF3 Activators open new avenues for investigating the intricacies of post-transcriptional gene regulation, providing researchers with valuable tools to dissect the functional consequences of manipulating YTHDF3 activity in diverse biological contexts.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Adenosine

58-61-7sc-291838
sc-291838A
sc-291838B
sc-291838C
sc-291838D
sc-291838E
sc-291838F
1 g
5 g
100 g
250 g
1 kg
5 kg
10 kg
$33.00
$47.00
$294.00
$561.00
$1020.00
$2550.00
$4590.00
1
(0)

Acts as a precursor for the m6A methylation pathway, potentially increasing YTHDF3 activation indirectly.

L-Methionine

63-68-3sc-394076
sc-394076A
sc-394076B
sc-394076C
sc-394076D
sc-394076E
25 g
100 g
250 g
1 kg
5 kg
10 kg
$33.00
$36.00
$56.00
$148.00
$566.00
$1081.00
(0)

It provides the methyl group in the m6A methylation pathway, indirectly activating YTHDF3.

Folic Acid

59-30-3sc-204758
10 g
$72.00
2
(1)

Participates in one-carbon metabolism that feeds into the methylation process of m6A, influencing YTHDF3 indirectly.

Vitamin B12

68-19-9sc-296695
sc-296695A
sc-296695B
sc-296695C
sc-296695D
sc-296695E
100 mg
1 g
5 g
25 g
100 g
1 kg
$39.00
$55.00
$204.00
$877.00
$3414.00
$9180.00
2
(1)

Participates in the synthesis of methionine which is a precursor to SAM, indirectly affecting the activation of YTHDF3.

Choline chloride

67-48-1sc-207430
sc-207430A
sc-207430B
10 mg
5 g
50 g
$32.00
$36.00
$51.00
1
(1)

It is metabolized to form betaine which aids in the synthesis of methionine, indirectly affecting YTHDF3 activation.

Betaine

107-43-7sc-214595
sc-214595A
sc-214595B
sc-214595C
sc-214595D
sc-214595E
50 g
100 g
250 g
1 kg
2.5 kg
5 kg
$30.00
$40.00
$55.00
$160.00
$330.00
$580.00
2
(1)

It donates a methyl group for the synthesis of methionine, indirectly influencing the m6A methylation pathway and YTHDF3 activation.

D-(+)-Biotin

58-85-5sc-204706
sc-204706A
sc-204706B
1 g
5 g
25 g
$40.00
$105.00
$326.00
1
(4)

Involved in the synthesis of methionine, indirectly influencing the m6A methylation pathway and YTHDF3 activation.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Acts as a co-factor for enzymes involved in methionine metabolism, indirectly influencing the activation of YTHDF3.

Selenium

7782-49-2sc-250973
50 g
$61.00
1
(1)

It can influence the expression of enzymes involved in methylation processes, indirectly affecting YTHDF3 activation.