YTHDF3 Activators belong to a distinctive chemical class that exerts its influence at the molecular level, specifically targeting the YTH domain family protein 3 (YTHDF3). YTHDF3 is a member of the YTH domain-containing family of proteins, which are integral players in the dynamic and intricate landscape of RNA metabolism. The YTHDF3 Activators operate by modulating the activity of YTHDF3, a critical component of the mRNA decay machinery. YTHDF3 is known for its involvement in the regulation of mRNA stability and degradation, thereby influencing the abundance of specific transcripts within the cellular environment.
YTHDF3 Activators are characterized by their ability to interact selectively with YTHDF3, often through intricate binding motifs that facilitate precise engagement with the protein's RNA recognition pockets. This interaction subsequently alters the conformation and functional dynamics of YTHDF3, leading to downstream effects on RNA processing and degradation. The nuanced control exerted by YTHDF3 Activators over these cellular processes underscores the importance of understanding the molecular mechanisms governing RNA fate and turnover. Given the pivotal role of YTHDF3 in shaping the cellular transcriptome, the development and exploration of YTHDF3 Activators open new avenues for investigating the intricacies of post-transcriptional gene regulation, providing researchers with valuable tools to dissect the functional consequences of manipulating YTHDF3 activity in diverse biological contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $47.00 $294.00 $561.00 $1020.00 $2550.00 $4590.00 | 1 | |
Acts as a precursor for the m6A methylation pathway, potentially increasing YTHDF3 activation indirectly. | ||||||
L-Methionine | 63-68-3 | sc-394076 sc-394076A sc-394076B sc-394076C sc-394076D sc-394076E | 25 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $36.00 $56.00 $148.00 $566.00 $1081.00 | ||
It provides the methyl group in the m6A methylation pathway, indirectly activating YTHDF3. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Participates in one-carbon metabolism that feeds into the methylation process of m6A, influencing YTHDF3 indirectly. | ||||||
Vitamin B12 | 68-19-9 | sc-296695 sc-296695A sc-296695B sc-296695C sc-296695D sc-296695E | 100 mg 1 g 5 g 25 g 100 g 1 kg | $39.00 $55.00 $204.00 $877.00 $3414.00 $9180.00 | 2 | |
Participates in the synthesis of methionine which is a precursor to SAM, indirectly affecting the activation of YTHDF3. | ||||||
Choline chloride | 67-48-1 | sc-207430 sc-207430A sc-207430B | 10 mg 5 g 50 g | $32.00 $36.00 $51.00 | 1 | |
It is metabolized to form betaine which aids in the synthesis of methionine, indirectly affecting YTHDF3 activation. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $30.00 $40.00 $55.00 $160.00 $330.00 $580.00 | 2 | |
It donates a methyl group for the synthesis of methionine, indirectly influencing the m6A methylation pathway and YTHDF3 activation. | ||||||
D-(+)-Biotin | 58-85-5 | sc-204706 sc-204706A sc-204706B | 1 g 5 g 25 g | $40.00 $105.00 $326.00 | 1 | |
Involved in the synthesis of methionine, indirectly influencing the m6A methylation pathway and YTHDF3 activation. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Acts as a co-factor for enzymes involved in methionine metabolism, indirectly influencing the activation of YTHDF3. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $61.00 | 1 | |
It can influence the expression of enzymes involved in methylation processes, indirectly affecting YTHDF3 activation. | ||||||