YSK1 Inhibitors
YSK1 inhibitors belong to a distinct chemical class of compounds that are specifically designed to target and modulate the activity of the protein kinase known as YSK1 (also called PRKX). YSK1 is a serine/threonine kinase that plays a crucial role in various cellular processes, including signal transduction and gene expression regulation. The inhibitors are meticulously designed molecules that can selectively bind to the active site of YSK1, disrupting its enzymatic function. By doing so, YSK1 inhibitors can effectively block the phosphorylation of downstream substrates that are essential for various cellular pathways. The chemical structure of YSK1 inhibitors is characterized by a specific arrangement of functional groups that allow for optimal interactions with the active site of the YSK1 kinase. The inhibitors are designed to have high affinity and selectivity towards YSK1, minimizing off-target effects on other kinases.
The development of YSK1 inhibitors involves extensive chemistry and structure-activity relationship studies to optimize their potency and pharmacological properties. These inhibitors hold great promise as valuable research tools in studying the molecular mechanisms involving YSK1 in cellular processes. By selectively inhibiting YSK1, researchers can gain valuable insights into the kinase's role in signaling cascades, cell proliferation, and gene regulation. Additionally, YSK1 inhibitors may have applications in further understanding various diseases where YSK1 dysregulation is implicated.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium (CAS 7439-93-2) functions as an inhibitor of the YSK1 protein, a member of the germinal center kinase family. In research, lithium is shown to inhibit YSK1 by interfering with its phosphorylation process, which is crucial for its activity in cellular signaling pathways. This inhibition aids in studying the regulatory mechanisms of YSK1 in various cellular processes such as stress response and cytoskeletal dynamics. | ||||||
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $71.00 $202.00 | 18 | |
A synthetic small molecule inhibitor that selectively targets GSK3B. It has been used in research to study the role of GSK3B in various cellular processes. | ||||||
GSK-3 Inhibitor XVI | 252917-06-9 | sc-221691 sc-221691A | 5 mg 25 mg | $180.00 $610.00 | 4 | |
Another synthetic small molecule inhibitor of GSK3B that has been widely used in research for its specificity and potency. | ||||||
GSK-3β Inhibitor VIII | 487021-52-3 | sc-202636 sc-202636A | 5 mg 10 mg | $134.00 $150.00 | 5 | |
A potent and selective ATP-competitive inhibitor of GSK3B, which has been utilized in research studies. | ||||||
GSK-3β Inhibitor I | 327036-89-5 | sc-221692 sc-221692A | 5 mg 25 mg | $183.00 $288.00 | 4 | |
GSK-3β Inhibitor I (CAS 327036-89-5) is a chemical compound known for its role in inhibiting the YSK1 protein. It functions by targeting specific phosphorylation sites, thereby regulating YSK1′s kinase activity. This inhibition is useful in studying signal transduction pathways and cellular processes where YSK1 is involved, offering valuable insights into its role in regulating cellular functions such as stress responses and protein interactions. | ||||||
Tideglusib | 865854-05-3 | sc-507358 | 10 mg | $77.00 | ||
Tideglusib (CAS 865854-05-3) is a potent inhibitor of YSK1, a kinase involved in cellular signaling pathways. By inhibiting YSK1 activity, Tideglusib disrupts key phosphorylation processes associated with kinase regulation. This inhibition provides valuable insights into YSK1′s role in cell signaling and has broad implications for understanding protein interactions and pathways in scientific research. | ||||||
AZD1080 | 612487-72-6 | sc-503187 | 2.5 mg | $280.00 | ||
AZD1080 (CAS 612487-72-6) is a potent and selective inhibitor of the YSK1 protein, a member of the Ste20-related kinase family. By targeting YSK1, AZD1080 disrupts its kinase activity, which plays a key role in regulating cellular processes such as stress response and cytoskeletal organization. This compound is widely used in research to study the molecular pathways involving YSK1 and its role in intracellular signaling networks. | ||||||
LY2090314 | 603288-22-8 | sc-507359 | 5 mg | $175.00 | ||
LY2090314 (CAS 603288-22-8) is a potent and selective inhibitor of the YSK1 protein, a kinase involved in cellular signaling pathways. LY2090314 functions by targeting the ATP-binding site of YSK1, thereby inhibiting its enzymatic activity. This compound is valuable in biochemical and molecular biology studies for exploring YSK1-related mechanisms and pathways, offering insight into the regulation of kinase signaling in various research applications. | ||||||
BIP-135 | 941575-71-9 | sc-364435 sc-364435A | 5 mg 25 mg | $105.00 $410.00 | ||
BIP-135 (CAS 941575-71-9) is a small molecule known for its role as an inhibitor of YSK1, a serine/threonine-protein kinase. By selectively binding to YSK1, BIP-135 disrupts its kinase activity, allowing researchers to study the downstream signaling pathways and biological processes regulated by YSK1. This compound is valuable for exploring YSK1′s function in cellular signaling and regulation. | ||||||