WISP-2 Activators
WISP-2 activators, as listed, are primarily chemicals that indirectly affect WISP-2 activity by targeting signaling pathways and cellular processes relevant to its function. WISP-2 is involved in complex cellular signaling networks, particularly those associated with the extracellular matrix and cell proliferation. The chemicals mentioned, such as Wnt pathway modulators (SKL2001, LiCl, BIO), TGF-β and BMP signaling inhibitors (SB431542, Dorsomorphin, A-83-01), and various signaling pathway modulators (PD98059, Y-27632, Forskolin, Rapamycin), act on different aspects of cellular signaling, potentially influencing the function of WISP-2.
These activators are significant in understanding the complex interactions within signaling networks related to cell growth, differentiation, and apoptosis. Modulating pathways like Wnt, TGF-β, and BMP can impact the cellular context in which WISP-2 operates, thereby influencing its role in these processes. For example, activating or inhibiting Wnt signaling can have downstream effects on WISP-2's function in tissue development and repair.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
LiCl activates Wnt signaling by inhibiting GSK-3β, which may affect WISP-2 related pathways. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
BIO is a GSK-3 inhibitor, potentially enhancing Wnt/β-catenin signaling and indirectly affecting WISP-2. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
SB431542 inhibits TGF-β signaling, which can intersect with pathways involving WISP-2, potentially influencing its function. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $96.00 $355.00 | 69 | |
Dorsomorphin inhibits BMP signaling, which may interact with WISP-2-related cellular processes. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an inhibitor of MEK, a kinase in the MAPK pathway, potentially impacting WISP-2 related signaling. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 inhibits ROCK, which can affect cytoskeletal dynamics and potentially influence WISP-2 mediated processes. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which can modulate various signaling pathways including those related to WISP-2. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR signaling, potentially impacting cellular processes and signaling pathways involving WISP-2. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
A-83-01 inhibits TGF-β type I receptor ALK5, potentially affecting signaling pathways relevant to WISP-2. | ||||||
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | $38.00 $79.00 $188.00 $520.00 $1248.00 $5930.00 | 8 | |
Niclosamide inhibits the Wnt/β-catenin signaling pathway, potentially impacting WISP-2-related processes in a context-dependent manner. | ||||||