WDR89 Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
This compound binds to FKBP12 and together they inhibit the mTOR pathway, which is essential for protein synthesis and cell growth. Inhibition of this pathway leads to reduced activity of downstream proteins including WDR89, affecting its function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A specific inhibitor of PI3K, leading to suppression of the AKT signaling pathway. This cascade is crucial for cell survival and growth; by inhibiting PI3K, the downstream effects result in decreased activity of proteins like WDR89. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Acts as a selective inhibitor of MEK1/2, effectively blocking the MAPK/ERK pathway. This pathway is involved in cell proliferation and differentiation, and its inhibition disrupts the functional activity of proteins involved, such as WDR89. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor that disrupts the p38 signaling pathway, which is involved in stress responses and cytokine production. Inhibiting this pathway impairs the activity of associated proteins, including WDR89. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $65.00 $267.00 | 257 | |
An inhibitor of JNK, modulating the JNK signaling pathway which affects processes like apoptosis and inflammation. By inhibiting this pathway, proteins that participate in these processes, like WDR89, are rendered less active. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A potent inhibitor of PI3K, leading to the cessation of the PI3K/AKT pathway. This interference results in a decrease in the functional activity of related proteins, such as WDR89. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Specifically inhibits MEK, which is part of the MAPK/ERK pathway. Disruption of this pathway affects cell cycle progression and growth, indirectly leading to decreased activity of proteins such as WDR89 involved in these processes. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor that affects cytoskeleton organization and cell motility by inhibiting the Rho/ROCK pathway. This leads to a decrease in the activity of related proteins, including WDR89. | ||||||
BIX 02189 | 1094614-85-3 | sc-364436 sc-364436A | 5 mg 10 mg | $220.00 $378.00 | 5 | |
Inhibits MEK5, which consequently affects the ERK5 pathway involved in cell proliferation and survival. By inhibiting this pathway, the activity of proteins involved in these processes, including WDR89, is decreased. | ||||||
MLN 4924 | 905579-51-3 | sc-484814 | 1 mg | $280.00 | 1 | |
This compound inhibits NEDD8-activating enzyme, which is essential for the neddylation process affecting protein degradation. By inhibiting this enzyme, the stability and function of proteins like WDR89 can be indirectly decreased. | ||||||