The chemicals listed are mostly hormones and signaling molecules that play crucial roles in the process of oocyte maturation. Activation of these compounds or the pathways they influence can demand increased VMO1 function to maintain vitelline membrane integrity. For example, Estradiol and Progesterone both are steroids that can modulate gene expression patterns related to oocyte maturation, affecting VMO1 indirectly by increasing the need for a robust and functional vitelline membrane.
On the other hand, chemicals like Forskolin and Cilostamide influence the cAMP pathway. Elevated cAMP levels are associated with oocyte maturation, a process that is inherently tied to the necessity for a well-formed vitelline membrane. Given VMO1's role in vitelline membrane formation, an increased demand for this membrane due to heightened oocyte maturation activity could logically necessitate an increase in VMO1 expression and function. Therefore, it's plausible to expect a subsequent rise in VMO1 activity in response to these chemicals, despite the indirect nature of their influence.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Estrogen receptor activator that upregulates genes associated with oocyte maturation; can theoretically increase the demand for vitelline membrane integrity, thus indirectly activating VMO1. | ||||||
Progesterone | 57-83-0 | sc-296138A sc-296138 sc-296138B | 1 g 5 g 50 g | $20.00 $51.00 $292.00 | 3 | |
Steroid hormone that plays a role in oocyte maturation; its elevated levels may necessitate enhanced vitelline membrane function, indirectly affecting VMO1. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylyl cyclase, increasing cAMP levels which play a role in oocyte maturation; could indirectly lead to enhanced VMO1 expression. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
Directly impacts oocyte maturation and could potentially increase the demand for VMO1 in maintaining vitelline membrane integrity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Involved in germ cell differentiation; could upregulate VMO1 indirectly through increased need for vitelline membrane. | ||||||
Cilostamide (OPC 3689) | 68550-75-4 | sc-201180 sc-201180A | 5 mg 25 mg | $90.00 $350.00 | 16 | |
Phosphodiesterase inhibitor; increases cAMP and may indirectly affect VMO1 through oocyte maturation pathways. | ||||||