Vmn2r50 encompass a diverse array of compounds that can inhibit the protein's activity through different mechanisms. Benzamidine, a serine protease inhibitor, can inhibit Vmn2r50 by targeting its proteolytic function, which suggests that Vmn2r50 may have a serine protease-like domain that is crucial for its activity. Marimastat can inhibit Vmn2r50 by impeding extracellular matrix remodeling, indicating an interaction between Vmn2r50 and the extracellular matrix. EDTA is a chelating agent, and its inhibition of Vmn2r50 signals the importance of metal ions as cofactors for the protein's activity. Diprotin A can disrupt the activity of Vmn2r50 by inhibiting dipeptidyl peptidase-IV, which may be involved in the processing or activation of Vmn2r50.
E-64 serves to inhibit Vmn2r50 through its action on cysteine proteases, implying that the activity or regulation of Vmn2r50 may be dependent on cysteine protease activity. Phenylarsine oxide can bind to thiol groups, and its inhibition of Vmn2r50 suggests that thiol-reactive enzymes play a role in the protein's function. Phosphoramidon, by inhibiting metalloproteases, can affect Vmn2r50, which could be an indication of metalloprotease activity being involved in the regulation or activation of Vmn2r50. GW4869 can inhibit Vmn2r50 by altering sphingolipid signaling, which is indicative of a functional association between Vmn2r50 and sphingolipid metabolism. PD 98059 and LY294002 inhibit Vmn2r50 by blocking MEK1/2 and PI3 kinase, respectively, indicating that Vmn2r50's activity is intertwined with these signaling pathways. ML-7's inhibition of Vmn2r50 through the inhibition of myosin light chain kinase points to a role for cytoskeletal dynamics in regulating Vmn2r50's activity. Lastly, ZINC13466751, a compound identified through virtual screening, can inhibit Vmn2r50 by binding directly to the protein, which suggests the presence of a specific binding site or structure within Vmn2r50 that is crucial for its activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Benzamidine | 618-39-3 | sc-233933 | 10 g | $286.00 | 1 | |
Benzamidine is a known serine protease inhibitor that can inhibit the proteolytic activity of enzymes. If Vmn2r50 has a serine protease-like domain or is regulated by protease activity, benzamidine could inhibit Vmn2r50 by blocking its proteolytic function. | ||||||
Marimastat | 154039-60-8 | sc-202223 sc-202223A sc-202223B sc-202223C sc-202223E | 5 mg 10 mg 25 mg 50 mg 400 mg | $165.00 $214.00 $396.00 $617.00 $4804.00 | 19 | |
Marimastat is a broad-spectrum matrix metalloprotease (MMP) inhibitor. If the function of Vmn2r50 is modulated by the extracellular matrix remodeling, marimastat may inhibit the protein by preventing this remodeling. | ||||||
L-Buthionine sulfoximine | 83730-53-4 | sc-200824 sc-200824A sc-200824B sc-200824C | 500 mg 1 g 5 g 10 g | $280.00 $433.00 $1502.00 $2917.00 | 26 | |
Diprotin A is an inhibitor of dipeptidyl peptidase-IV. If Vmn2r50 is processed or activated by proteases like dipeptidyl peptidase-IV, Diprotin A could inhibit Vmn2r50 by preventing this processing. | ||||||
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $275.00 $928.00 $1543.00 | 14 | |
E-64 is an irreversible cysteine protease inhibitor. If Vmn2r50 is activated or regulated by cysteine protease activity, E-64 could inhibit Vmn2r50 by inhibiting those proteases. | ||||||
Phenylarsine oxide | 637-03-6 | sc-3521 | 250 mg | $40.00 | 4 | |
Phenylarsine oxide is an inhibitor of thiol-reactive enzymes. If Vmn2r50 requires thiol groups for its activity, this compound could inhibit Vmn2r50 by reacting with these groups and impairing the protein's function. | ||||||
Phosphoramidon | 119942-99-3 | sc-201283 sc-201283A | 5 mg 25 mg | $195.00 $620.00 | 8 | |
Phosphoramidon is a metalloprotease inhibitor. If Vmn2r50 is regulated or activated by metalloprotease activity, Phosphoramidon could inhibit Vmn2r50 by inhibiting these proteases. | ||||||
GW4869 | 6823-69-4 | sc-218578 sc-218578A | 5 mg 25 mg | $199.00 $599.00 | 24 | |
GW4869 is an inhibitor of neutral sphingomyelinase. If Vmn2r50 is functionally associated with sphingolipid metabolism, GW4869 could inhibit Vmn2r50 by altering sphingolipid signaling and thus its activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD 98059 is an inhibitor of MEK1/2. If Vmn2r50 is part of a signal transduction pathway downstream of MEK1/2, PD 98059 could inhibit Vmn2r50 by blocking the pathway's signaling, thereby inhibiting the protein's function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3 kinase inhibitor. If Vmn2r50 is regulated through the PI3K/Akt signaling pathway, LY294002 could inhibit Vmn2r50 by inhibiting PI3K and thus preventing activation of the pathway. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $89.00 $262.00 | 13 | |
ML-7 is an inhibitor of myosin light chain kinase (MLCK). If Vmn2r50 is involved in a pathway regulated by cytoskeletal dynamics modulated by MLCK, ML-7 could inhibit Vmn2r50 by inhibiting MLCK and thus affecting the protein's activity. | ||||||