Vgl-3 Activators
VGLL3 protein is a cofactor involved in transcription regulation, interacting with transcription factors from the TEAD family. The TEAD-VGLL3 complex binds to specific DNA sequences, modulating the expression of target genes. This process is important for various cellular processes, including cell proliferation and differentiation.Studies suggest that VGLL3 plays roles in immune system function and developmental processes. For instance, it's implicated in sex-biased autoimmune diseases, such as lupus, where its overexpression in females is thought to contribute to the higher incidence of disease.
In developmental biology, VGLL3 is thought to play a role in the formation of muscle tissue, given the homology to 'vestigial', a protein associated with wing development in fruit flies.VGLL3 is also implicated in cancer biology. Overexpression of VGLL3 has been found in certain types of cancer, including squamous cell carcinoma, where it is thought to contribute to tumorigenesis by promoting cell proliferation and inhibiting apoptosis.In short, VGLL3 is a multifunctional protein with roles in gene regulation, development, immune response, and potentially cancer.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid, a metabolite of Vitamin A, plays a crucial role in gene transcription and could indirectly influence VGLL3 by modulating transcription factors and pathways. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D, through its active form, influences transcription regulation and could have an indirect effect on VGLL3 activity in differentiation and development. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin, which activates adenylate cyclase, leading to increased cAMP levels, could indirectly influence VGLL3 through cAMP-dependent signaling pathways. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
As a glucocorticoid, Dexamethasone affects gene expression and could indirectly impact VGLL3 activity through its regulatory effects on transcription factors. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, 5-Azacytidine, may indirectly influence VGLL3 by altering the methylation status of genes and affecting transcription. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, Trichostatin A could indirectly affect VGLL3 by altering chromatin structure and gene expression. | ||||||