VAM1 Activators
N-Ethylmaleimide (NEM) and toxins like Tetanus Toxin and Botulinum Toxin directly target components of the SNARE complex, crucial for vesicle fusion events. VAM1's involvement in SNARE-mediated processes implies that these compounds could significantly impact its function. Similarly, the inhibition of dynamin by Dynasore and can affect vesicle formation and trafficking, thereby influencing VAM1's role in these processes.
Wortmannin and Cytochalasin D and Jasplakinolide, which modulate actin dynamics, provide insights into the involvement of VAM1 in signaling pathways and cytoskeletal interactions that are crucial for vesicular movement and fusionThese compounds, through their varied actions on vesicle transport, SNARE complex formation, and cytoskeletal dynamics, highlight the complex nature of VAM1's functions in cellular vesicular transport processes.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Inhibits protein transport between the endoplasmic reticulum and Golgi apparatus, potentially affecting VAM1's role in vesicular trafficking. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
A sodium ionophore that disrupts Golgi function, possibly impacting VAM1's involvement in vesicle transport and processing. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $69.00 $214.00 $796.00 $1918.00 | 19 | |
Inhibits SNARE complex formation, which could impact VAM1's function in vesicle docking and fusion processes. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inhibits N-linked glycosylation, potentially affecting VAM1's role in protein trafficking and glycoprotein processing. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Inhibits dynamin, potentially impacting vesicular budding processes where VAM1 might be involved. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Disrupts actin filaments, possibly affecting VAM1's function in actin-dependent vesicular transport. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Stabilizes actin filaments, potentially impacting VAM1's role in vesicular movement along the cytoskeleton. | ||||||