UGT2B36 Inhibitors
The chemical class referred to as UGT2B36 inhibitors encompasses a diverse range of compounds that present unique strategies for the modulation of UGT2B36. Although direct inhibitors for this enzyme have not been identified, these compounds offer indirect avenues by influencing cellular signaling pathways and conditions that could impact the expression or activity of UGT2B36. Sulfinpyrazone, classified as a uricosuric agent, indirectly modulates UGT2B36 by reducing uric acid levels through a mechanism involving the reduction of renal tubule reabsorption. Flavonoids with antioxidant properties, such as Quercetin and Ellagic Acid, exert their influence on UGT2B36 by modulating redox-sensitive pathways. Fenofibrate, known as a PPARα agonist, activates PPARα, thereby affecting the expression of UGT2B36. Additionally, compounds like Naringenin, Andrographolide, Curcumin, Genistein, Silibinin, 5-Aminosalicylic Acid, and Alpha-Lipoic Acid each provide distinct pathways for UGT2B36 modulation, targeting processes such as inflammation, oxidative stress, and cellular signaling.
This array of compounds, each characterized by its unique mechanism of action, collectively forms a comprehensive toolkit for researchers to delve into the intricate regulatory network governing UGT2B36. Despite the absence of identified direct inhibitors, these compounds offer valuable insights into indirect modulation, paving the way for a deeper understanding of UGT2B36's functional relevance in various cellular contexts. Their nuanced effects on cellular processes not only contribute to the elucidation of UGT2B36's role but also hold promise for future investigations into interventions that may leverage the intricate interplay between these compounds and UGT2B36 in a targeted manner.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(±)-Sulfinpyrazone | 57-96-5 | sc-202822 sc-202822A | 1 g 5 g | $39.00 $92.00 | 2 | |
Sulfinpyrazone is a uricosuric agent that indirectly influences UGT2B36 by modulating uric acid metabolism. It reduces uric acid reabsorption in the renal tubules, promoting its excretion. The altered uric acid levels may impact UGT2B36 activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid, affects UGT2B36 indirectly by modulating cellular signaling pathways. Its antioxidant properties influence redox-sensitive pathways, potentially impacting UGT2B36 expression or activity. The compound's broad effects on cellular processes offer a nuanced approach to UGT2B36 modulation. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Ellagic Acid is a polyphenol that indirectly modulates UGT2B36. It influences cellular pathways related to oxidative stress and inflammation. By altering these pathways, ellagic acid may indirectly impact UGT2B36 activity, providing a unique avenue for regulation. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
Fenofibrate, a PPARα agonist, indirectly modulates UGT2B36 by activating PPARα. This nuclear receptor regulates various metabolic pathways, potentially influencing UGT2B36 expression or activity. The compound's specificity for PPARα offers a targeted approach to UGT2B36 modulation. | ||||||
Naringenin | 480-41-1 | sc-219338 | 25 g | $245.00 | 11 | |
Naringenin, a flavonoid, indirectly modulates UGT2B36 by influencing cellular signaling pathways. Its interaction with various kinases and receptors may impact UGT2B36 expression or activity. The compound's ability to target specific pathways offers a tailored approach to UGT2B36 modulation. | ||||||
Andrographolide | 5508-58-7 | sc-205594 sc-205594A | 50 mg 100 mg | $15.00 $39.00 | 7 | |
Andrographolide, a labdane diterpenoid, indirectly modulates UGT2B36 by influencing inflammatory pathways. Its anti-inflammatory properties may alter cellular conditions, impacting UGT2B36 expression or activity. The compound's specificity for inflammation-related pathways provides a targeted approach to UGT2B36 modulation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, a polyphenol, indirectly modulates UGT2B36 through its influence on cellular signaling pathways. Its modulation of NF-κB and other pathways may impact UGT2B36 expression or activity. The compound's multifaceted effects on cellular processes offer a nuanced strategy for UGT2B36 regulation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, an isoflavone, indirectly modulates UGT2B36 by affecting cellular signaling pathways. Its interaction with various kinases and receptors may influence UGT2B36 expression or activity. The compound's ability to target specific pathways provides a tailored approach to UGT2B36 modulation. | ||||||
Silybin | 22888-70-6 | sc-202812 sc-202812A sc-202812B sc-202812C | 1 g 5 g 10 g 50 g | $54.00 $112.00 $202.00 $700.00 | 6 | |
Silibinin, a flavonolignan, indirectly modulates UGT2B36 through its impact on cellular signaling pathways. Its modulation of inflammatory and oxidative stress pathways may influence UGT2B36 expression or activity. The compound's specificity for these pathways offers a targeted approach to UGT2B36 modulation. | ||||||
5-Aminosalicylic acid | 89-57-6 | sc-202890 | 5 g | $26.00 | 4 | |
5-Aminosalicylic Acid indirectly influences UGT2B36 through its anti-inflammatory properties. By modulating inflammatory pathways, it may alter cellular conditions, impacting UGT2B36 expression or activity. The compound's specificity for inflammation-related pathways provides a targeted approach to UGT2B36 modulation. | ||||||