TUSC1 inhibitors are a class of chemical compounds designed to specifically target and inhibit the function of the Tumor Suppressor Candidate 1 (TUSC1) protein. TUSC1 is a relatively lesser-known protein believed to play a role in various cellular processes, including cell proliferation, apoptosis, and the maintenance of cellular structure. The precise biological function of TUSC1 is not fully understood, but it is thought to be involved in regulatory networks that maintain normal cellular homeostasis. By inhibiting TUSC1, researchers can disrupt its activity and observe how it affects various molecular pathways, which may include interactions with other cellular proteins or involvement in gene regulation mechanisms.
Structurally, TUSC1 inhibitors are designed to interact with specific functional domains of the protein, potentially blocking its interactions with other proteins or preventing it from carrying out its role in cellular signaling. These inhibitors could target key binding sites, affecting the protein's stability or its ability to participate in regulatory complexes. By inhibiting TUSC1, researchers can investigate the protein's role in cellular function and its contribution to maintaining normal cell behavior. The use of these inhibitors allows for detailed studies into the molecular mechanisms governed by TUSC1, particularly in areas related to cell cycle regulation, signal transduction, and cellular stress responses. This research provides insights into the broader implications of TUSC1's activity and how its inhibition can impact fundamental cellular processes, contributing to a deeper understanding of protein interactions and regulatory networks within cells.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Erlotinib, Free Base | 183321-74-6 | sc-396113 sc-396113A sc-396113B sc-396113C sc-396113D | 500 mg 1 g 5 g 10 g 100 g | $85.00 $132.00 $287.00 $495.00 $3752.00 | 42 | |
EGFR inhibitor; can downregulate pathways where TUSC1 may be involved, affecting cell proliferation. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Raf kinase inhibitor; can impact MAPK/ERK signaling, potentially altering TUSC1-related pathways. | ||||||
Sunitinib, Free Base | 557795-19-4 | sc-396319 sc-396319A | 500 mg 5 g | $150.00 $920.00 | 5 | |
Receptor tyrosine kinase inhibitor; can affect angiogenesis and cell growth pathways involving TUSC1. | ||||||
Zoledronic acid, anhydrous | 118072-93-8 | sc-364663 sc-364663A | 25 mg 100 mg | $90.00 $251.00 | 5 | |
Bisphosphonate; can impact prenylation, affecting the localization and function of proteins, including TUSC1. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Proteasome inhibitor; can affect protein degradation pathways, potentially altering TUSC1 levels. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Modulates degradation of transcription factors; can indirectly affect TUSC1 by altering gene expression. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
MDM2 inhibitor; can stabilize p53, affecting cell cycle pathways that TUSC1 may be part of. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
HDAC inhibitor; can change chromatin structure and gene expression, possibly affecting TUSC1 function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor; can affect cell growth and autophagy, potentially impacting TUSC1-related processes. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000 sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E | 1 g 5 g 10 g 50 g 100 g 250 g | $30.00 $42.00 $62.00 $153.00 $255.00 $500.00 | 37 | |
AMPK activator; can alter metabolic pathways, which may intersect with TUSC1's function in the cell. |