TTYH1 Activators
TTYH1, standing for Tweety Family Member 1, is a gene that encodes a protein part of the Tweety family of proteins. These proteins are characterized by their multiple transmembrane domains, suggesting a role in ion transport across cellular membranes.The TTYH1 protein is predominantly expressed in the brain and has been implicated in various neurological functions. Its structure suggests it functions as a chloride channel or chloride channel regulator, which is essential for maintaining ion balance and cell volume regulation in neurons. Proper ion balance is crucial for neuronal excitability, signaling, and overall brain function.
Research has explored TTYH1's involvement in neural development and its role in neurodevelopmental disorders. The protein's expression in the brain and its presumed function in ion transport make it a candidate for influencing processes like neuron differentiation, migration, and synaptic formation.
TTYH1 has also been associated with pathological conditions. Its altered expression or function might contribute to the development of certain neurological diseases, such as epilepsy or neurodegenerative disorders. These diseases often involve disruptions in ion homeostasis and neuronal signaling, processes in which TTYH1 could play a critical role.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bumetanide (Ro 10-6338) | 28395-03-1 | sc-200727 sc-200727A | 1 g 5 g | $107.00 $224.00 | 9 | |
A loop diuretic inhibiting the Na⁺-K⁺-2Cl⁻ cotransporter, potentially affecting ion transport processes relevant to TTYH1. | ||||||
Furosemide | 54-31-9 | sc-203961 | 50 mg | $40.00 | ||
Another loop diuretic, similar in action to bumetanide, could indirectly influence TTYH1 activity. | ||||||
Hydrochlorothiazide | 58-93-5 | sc-207738 sc-207738A sc-207738B sc-207738C sc-207738D | 5 g 25 g 50 g 100 g 250 g | $54.00 $235.00 $326.00 $551.00 $969.00 | ||
A thiazide diuretic affecting sodium transport, could have implications for TTYH1-related ion transport. | ||||||
Amiloride | 2609-46-3 | sc-337527 | 1 g | $290.00 | 7 | |
Inhibits epithelial sodium channels, potentially impacting ion transport mechanisms associated with TTYH1. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $107.00 | 3 | |
An aldosterone antagonist with diuretic effects, might influence ion transport and hence TTYH1 activity. | ||||||
Ouabain-d3 (Major) | sc-478417 | 1 mg | $506.00 | |||
Inhibits the Na⁺/K⁺-ATPase pump, potentially impacting ion homeostasis and indirectly affecting TTYH1. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $367.00 | ||
A calcium channel blocker, could indirectly affect ion transport and processes related to TTYH1. | ||||||
Glyburide (Glibenclamide) | 10238-21-8 | sc-200982 sc-200982A sc-200982D sc-200982B sc-200982C | 1 g 5 g 25 g 100 g 500 g | $45.00 $60.00 $115.00 $170.00 $520.00 | 36 | |
An ATP-sensitive potassium channel inhibitor, potentially influencing ion transport mechanisms relevant to TTYH1. | ||||||
Niflumic acid | 4394-00-7 | sc-204820 | 5 g | $31.00 | 3 | |
A nonsteroidal anti-inflammatory drug that can inhibit chloride channels, potentially affecting TTYH1-related processes. | ||||||
Taurine | 107-35-7 | sc-202354 sc-202354A | 25 g 500 g | $47.00 $100.00 | 1 | |
May modulate cell volume and ion transport, potentially influencing TTYH1 function. | ||||||