TTLL10 activators belong to a distinct category of chemical compounds that have garnered attention in the field of molecular biology and genetics. These compounds are designed to modulate the activity of TTLL10, a gene that plays a role in various cellular processes. TTLL10, or Tubulin Tyrosine Ligase-Like Family Member 10, is a protein-coding gene that encodes for an enzyme involved in the post-translational modification of microtubules. Microtubules are crucial components of the cytoskeleton, providing structural support and serving as tracks for intracellular transport. TTLL10 activators work by targeting specific regulatory elements associated with the TTLL10 gene, often found in promoter or enhancer regions, to enhance its transcription and subsequent translation into functional protein products.
The mechanisms by which TTLL10 activators exert their effects may vary, but their primary function is to act as molecular switches that augment the activity of TTLL10. Research into the potential applications and implications of TTLL10 activation continues, with scientists striving to gain a deeper understanding of how this gene contributes to cellular processes and functions. This class of compounds holds promise for advancing our knowledge of gene regulation, particularly as it relates to microtubule dynamics and their significance in cellular development and intracellular transport processes. TTLL10 activators represent a valuable tool in the ongoing exploration of molecular biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Paclitaxel stabilizes microtubules, potentially increasing cellular demand for microtubule-associated proteins, possibly upregulating TTLL10. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubules, which could trigger compensatory mechanisms in the cell, potentially upregulating TTLL10 expression. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $39.00 $59.00 $104.00 $206.00 | 8 | |
Compounds like Geldanamycin induce heat shock proteins, which could lead to a stress response potentially affecting TTLL10 expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
HDAC inhibitors like Vorinostat alter chromatin structure, potentially enhancing the transcription of genes including TTLL10. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
By inhibiting proteasome activity, Bortezomib can induce cellular stress responses, potentially upregulating TTLL10 expression. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
Oxidative stress can activate signaling pathways that may lead to the upregulation of genes involved in stress responses, including TTLL10. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
By inhibiting mTOR, Rapamycin may affect protein synthesis and cellular stress pathways, potentially influencing TTLL10 expression. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AMPK activators like AICAR can enhance cellular energy stress responses, potentially leading to upregulation of TTLL10. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
By increasing intracellular calcium levels, A23187 may activate signaling pathways that could lead to upregulation of TTLL10. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Tunicamycin induces ER stress, potentially affecting protein folding and leading to a stress response that may upregulate TTLL10. | ||||||