TSHZ3 activators refer to a class of chemical compounds or molecules that have the ability to modulate the activity of the transcription factor Teashirt Zinc Finger Homeobox 3 (TSHZ3). TSHZ3 is a key regulatory protein involved in gene expression and developmental processes across multicellular organisms, including humans. Transcription factors, like TSHZ3, exert their influence on gene expression by binding to specific regions within DNA and either activating or repressing the transcription of target genes. TSHZ3 belongs to the TSHZ family of transcription factors and is characterized by the presence of zinc finger and homeobox domains, which are essential for DNA binding and the subsequent regulation of gene expression. Activators of TSHZ3 are compounds that can alter TSHZ3's transcriptional activity, thus playing a pivotal role in various biological contexts.
The activation of TSHZ3 by these compounds likely involves mechanisms that enhance its ability to bind to specific DNA sequences, interact with co-factors, or undergo post-translational modifications. Consequently, this modulation of TSHZ3 activity can lead to significant alterations in cellular processes by influencing the expression of its target genes. This makes TSHZ3 activators crucial components in unraveling the intricate regulatory networks that govern processes such as development, tissue homeostasis, and cellular differentiation. Understanding these activators contributes to a deeper comprehension of molecular mechanisms underlying biological processes and their relevance in various physiological and pathological conditions. It offers valuable insights into the complex world of gene regulation and its implications for diverse fields like developmental biology and molecular genetics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a derivative of vitamin A, can modulate gene expression and may induce TSHZ3 as part of differentiation pathways in certain cell types. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
By raising intracellular cAMP levels, forskolin can activate PKA, which may influence the transcription of development-associated genes like TSHZ3. | ||||||
Harmine | 442-51-3 | sc-202644 sc-202644A sc-202644B sc-202644C sc-202644D sc-202644E sc-202644F | 250 mg 500 mg 1 g 10 g 50 g 100 g 500 g | $52.00 $102.00 $124.00 $540.00 $1438.00 $2560.00 $11230.00 | 2 | |
Stabilizing β-catenin can activate Wnt signaling, which may result in increased TSHZ3 expression during cellular proliferation and differentiation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
As a glucocorticoid, dexamethasone can affect transcriptional regulation, potentially influencing the expression of TSHZ3. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
This histone deacetylase inhibitor can alter chromatin structure, possibly upregulating TSHZ3 expression by making its promoter more accessible. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methylation inhibitor can change gene expression patterns, possibly inducing TSHZ3 expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As an HDAC inhibitor, sodium butyrate can lead to histone hyperacetylation and may enhance the expression of genes like TSHZ3. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR activates AMPK, which can lead to cellular stress responses, potentially including the upregulation of TSHZ3. | ||||||
Bis(pinacolato)diboron | 73183-34-3 | sc-252467 sc-252467A | 1 g 5 g | $43.00 $80.00 | ||
Platelet-derived growth factor can induce signaling pathways associated with cell growth, which may include TSHZ3 expression. | ||||||