Date published: 2025-10-25

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TSHZ3 Activators

TSHZ3 activators refer to a class of chemical compounds or molecules that have the ability to modulate the activity of the transcription factor Teashirt Zinc Finger Homeobox 3 (TSHZ3). TSHZ3 is a key regulatory protein involved in gene expression and developmental processes across multicellular organisms, including humans. Transcription factors, like TSHZ3, exert their influence on gene expression by binding to specific regions within DNA and either activating or repressing the transcription of target genes. TSHZ3 belongs to the TSHZ family of transcription factors and is characterized by the presence of zinc finger and homeobox domains, which are essential for DNA binding and the subsequent regulation of gene expression. Activators of TSHZ3 are compounds that can alter TSHZ3's transcriptional activity, thus playing a pivotal role in various biological contexts.

The activation of TSHZ3 by these compounds likely involves mechanisms that enhance its ability to bind to specific DNA sequences, interact with co-factors, or undergo post-translational modifications. Consequently, this modulation of TSHZ3 activity can lead to significant alterations in cellular processes by influencing the expression of its target genes. This makes TSHZ3 activators crucial components in unraveling the intricate regulatory networks that govern processes such as development, tissue homeostasis, and cellular differentiation. Understanding these activators contributes to a deeper comprehension of molecular mechanisms underlying biological processes and their relevance in various physiological and pathological conditions. It offers valuable insights into the complex world of gene regulation and its implications for diverse fields like developmental biology and molecular genetics.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid, a derivative of vitamin A, can modulate gene expression and may induce TSHZ3 as part of differentiation pathways in certain cell types.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

By raising intracellular cAMP levels, forskolin can activate PKA, which may influence the transcription of development-associated genes like TSHZ3.

Harmine

442-51-3sc-202644
sc-202644A
sc-202644B
sc-202644C
sc-202644D
sc-202644E
sc-202644F
250 mg
500 mg
1 g
10 g
50 g
100 g
500 g
$52.00
$102.00
$124.00
$540.00
$1438.00
$2560.00
$11230.00
2
(2)

Stabilizing β-catenin can activate Wnt signaling, which may result in increased TSHZ3 expression during cellular proliferation and differentiation.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

As a glucocorticoid, dexamethasone can affect transcriptional regulation, potentially influencing the expression of TSHZ3.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

This histone deacetylase inhibitor can alter chromatin structure, possibly upregulating TSHZ3 expression by making its promoter more accessible.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This DNA methylation inhibitor can change gene expression patterns, possibly inducing TSHZ3 expression.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

As an HDAC inhibitor, sodium butyrate can lead to histone hyperacetylation and may enhance the expression of genes like TSHZ3.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$60.00
$270.00
$350.00
48
(2)

AICAR activates AMPK, which can lead to cellular stress responses, potentially including the upregulation of TSHZ3.

Bis(pinacolato)diboron

73183-34-3sc-252467
sc-252467A
1 g
5 g
$43.00
$80.00
(0)

Platelet-derived growth factor can induce signaling pathways associated with cell growth, which may include TSHZ3 expression.